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... omental pouch is created and the islets are adhered through adding calcium and thrombin to the plasma or an FDA-approved topical foam hemostatic agent resulting in coagulation to the omentum. The omental edges of the "bowl" are then closed with a running suture and marked with surgical clips for later localization (Figure 2). Closure of the pouch with non-absorbable suture was suggested by Ao et al. who reported early graft failure in a dog autograft recipient whose pouch had opened which they hypothesized led to damage capillaries supplying islets leading to necrosis [81]. ...

Citations

... As a final theme in this special issue, connotated researchers in the field propose several approaches to advance cutting edge technology and novel surgical techniques, as well as potentially limitless sources of tissue for β-cell replacement therapies. In an exhaustive review of the literature, Coughlan et al. [15] provide a balanced assessment of the current evidence with extrahepatic islet transplantation, including past and ongoing clinical trials. This article underscores the fact that, whilst preclinical evidence shows efficacy, much work remains for the successful clinical translation of extrahepatic islet transplantation. ...
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strong>Editorial Islet Transplantation: How Much Have We Advanced and How to Keep Moving Forward? Braulio A. Marfil-Garza <sup>1</sup>, Tatsuya Kin <sup>1, 2, *</sup> 1. Clinical Islet Transplant Program, University of Alberta, Edmonton, Alberta, Canada; E-Mails: marfilga@ualberta.ca ; tkin@ualberta.ca 2. Alberta Islet Distribution Program, Clinical Islet Laboratory, Edmonton, Alberta, Canada * Correspondence: Tatsuya Kin ; E-Mail: tkin@ualberta.ca Academic Editor: Haval Shirwan Special Issue : Current Advancement of Islet Cell Transplantation in the Treatment of Diabetes Mellitus OBM Transplantation 2022, volume 6, issue 4doi:10.21926/obm.transplant.2204171 Received: December 11, 2022 Accepted: December 18, 2022 Published: December 20, 2022