Muscle and joint amyloidosis with multiple myeloma. (a) Ulcerating shoulder swelling (b) Shoulder radiograph with ill-defined lytic lesions (c) CT scan showing muscle hypertrophy (d) Bone marrow with plasmacytosis (e) Muscle biopsy (congo red) (f) Apple green birefringence under polarized light 

Muscle and joint amyloidosis with multiple myeloma. (a) Ulcerating shoulder swelling (b) Shoulder radiograph with ill-defined lytic lesions (c) CT scan showing muscle hypertrophy (d) Bone marrow with plasmacytosis (e) Muscle biopsy (congo red) (f) Apple green birefringence under polarized light 

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The shoulder joint may be involved in seronegative spondyloarthropathy, calcium pyrophosphate dihydrate disease and degenerative joint disease. Adhesive capsulitis, calcific tendonitis and rotator cuff degeneration are other diseases that can involve the shoulder. The shoulder joint area may be involved as a consequence of extra-articular disease,...

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Neuropathic arthropathy (NA) is a long-term progressive disorder that causes joint destruction in the existence of a neurologic deficit. Minor injuries and fractures are commonly overlooked until the visible joint deterioration becomes persistent. Syringomyelia is one of the important causes of NA. The appearance of clinical signs in syringomyelia is caused by longitudinal cysts formed in the cervical and cervicothoracic regions of the spinal cord. Depending on the existence of the underlying disorder, the number and localization of the syrinxes, a range of symptoms, involving pain, sensation deficit, loss of motor function, and deep tendon reflex abnormality, emerge. The case is here described of a 68-year-old female patient with shoulder NA following syringomyelia, who partially responded to the rehabilitation program. Furthermore, the available case reports were comprehensively reviewed on Web of Science, Scopus, and PubMed/Medline. Furthermore, the available case reports were comprehensively evaluated on Web of Science, Scopus, and PubMed/Medline. Thus, we aimed to present the demographic characteristics, symptoms, physical examination signs, treatment, and follow-up parameters of syringomyelia-related shoulder NA cases.