Fig 6 - available via license: Creative Commons Attribution-NonCommercial 4.0 International
Content may be subject to copyright.
MRI findings of holoprosencephaly in a 34-week, 2-day fetus. (a) Axial HASTE image reveals fusion of the frontal lobes across the midline (white arrow). (b) Coronal HASTE image also depicts fusion of the frontal lobes across the midline (white arrow).
Source publication
Intracranial abnormalities are commonly suspected findings on antenatal ultrasound that require evaluation by magnetic resonance imaging. This review depicts multiple abnormalities imaged as a means to guide clinicians in proper diagnosis.
Context in source publication
Context 1
... occurs when there is failed or incomplete cleavage of the prosencephalon (Fig. 6). MRI is indicated to define the severity of fusion and associated anomalies. The most severe form is alobar holoprosencephaly, which manifests as a primitive monoventricle, absent interhemispheric fissure, and thalamic fusion. In semilobar holoprosencephaly, the anterior frontal lobes are fused, but the posterior interhemispheric ...
Similar publications
Deep learning is one of the most popular artificial intelligence techniques used in the medical field. Although it is at an early stage compared to deep learning analyses of computed tomography or magnetic resonance imaging, studies applying deep learning to ultrasound imaging have been actively conducted. This review analyzes recent studies that a...
Citations
... Most CNS anomalies are identified using 2/3D neurosonography performed by an experienced examiner (83.7% of CNS malformations were identified in this way), while fetal MRI is used only in limited cases [21][22][23]. However, although there are controversial reports on the management of CNS anomalies, some studies show that fetal MRI increases the accuracy of detecting CNS anomalies [24][25][26][27]. ...
Brain asymmetry is a hallmark of the human brain. Recent studies report a certain degree of abnormal asymmetry of brain lateralization between left and right brain hemispheres can be associated with many neuropsychiatric conditions. In this regard, some questions need answers. First, the accelerated brain asymmetry is programmed during the pre-natal period that can be called “accelerated brain decline clock”. Second, can we find the right biomarkers to predict these changes? Moreover, can we establish the dynamics of these changes in order to identify the right time window for proper interventions that can reverse or limit the neurological decline? To find answers to these questions, we performed a systematic online search for the last 10 years in databases using keywords. Conclusion: we need to establish the right in vitro model that meets human conditions as much as possible. New biomarkers are necessary to establish the “good” or the “bad” borders of brain asymmetry at the epigenetic and functional level as early as possible.
Fetal magnetic resonance imaging (MRI) has become a widely used tool in clinical practice, providing increased accuracy in prenatal diagnoses of congenital abnormalities of the brain, allowing for more accurate prenatal counseling, optimization of perinatal management, and in some cases fetal intervention. In this article, a brief description of how fetal ultrasound (US) and fetal MRI are used in clinical practice will be followed by an overview of the most common reasons for referral for fetal MRI of the brain, including ventriculomegaly, absence of the cavum septi pellucidi (CSP) and posterior fossa anomalies.
