Linear regression curve demonstrating the relationship between gestational age at delivery (or miscarriage) and the initial number of fetuses. 

Linear regression curve demonstrating the relationship between gestational age at delivery (or miscarriage) and the initial number of fetuses. 

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Objectives: To compare pregnancy outcomes between high-order multiple pregnancies resulting from assisted reproductive technology (ART) reduced to twins and non-reduced pregnancies, and to evaluate indications for using ART. Methods: This is a descriptive retrospective review of women with high-order multiple pregnancies reduced to twin carried...

Context in source publication

Context 1
... the study group, 83% of the miscarriages occurred in women carrying 4 or more fetuses initially. As the initial number of fetuses increased, the risk of preterm delivery increased, and the gestational age at delivery decreased (Figure 1). Table 2 demonstrates the pregnancy outcomes of both groups. ...

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Citations

... A few case reports have described treatment of heterotopic CSP viable pregnancies with local injection of potassium chloride. This method is commonly used for fetal reduction in multiple pregnancy [7][8][9]. Treatment with potassium chloride is associated with an increased risk of abdominal pain, pregnancy loss, excessive vaginal bleeding, prematurity, need for subsequent surgery, and spontaneous rupture of membranes and subsequent chorioamnionitis [1,[8][9][10][11][12]. ...
... This method is commonly used for fetal reduction in multiple pregnancy [7][8][9]. Treatment with potassium chloride is associated with an increased risk of abdominal pain, pregnancy loss, excessive vaginal bleeding, prematurity, need for subsequent surgery, and spontaneous rupture of membranes and subsequent chorioamnionitis [1,[8][9][10][11][12]. ...
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Background: Heterotopic pregnancy with a combination of a caesarean scar pregnancy and an intrauterine pregnancy is rare and has potentially life-threatening complications. Case presentation: We describe the case of a 27-year-old white woman who had experienced an emergency caesarean delivery at 39 weeks for fetal distress with no postpartum complications. This is a report of the successful expectant management of a heterotopic scar pregnancy. The gestational sac implanted into the scar area was non-viable. The woman was treated expectantly and had a normal vaginal delivery at 37 weeks of gestation. Conclusion: Expectant management under close monitoring can be appropriate in small non-viable heterotopic caesarean scar pregnancies.
... Gleicher et al. [13,14] in their review article revised the risk posed by twin gestation against singleton. They conclude that, in terms of risks and cost effectiveness, twin pregnancies represent an entirely reasonable option for IVF patients. ...
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Objectives . This study aims to evaluate perinatal outcomes such as gestational age at delivery and live birth rate in singleton and twin gestation with or without fetal reduction. Method . A retrospective analysis was done on patients which were divided into reduced and unreduced groups on the basis of order of reduction of one or more fetuses between 6 and 13 weeks of gestation. Patients records were studied to note gestational age at delivery/abortion, birth weight, and neonatal outcome. Result . The cohort included a total of 292 patients: 102 singletons and 190 twins. 52 pregnancies were reduced in singleton cohort and 68 were reduced in twin cohort. No statistical difference was observed in live birth rate, gestational age at delivery, and birth weight and significant higher incidence of IUGR was observed in reduced and unreduced twin gestation. In singleton pregnancies however preterm delivery rate increased with fetal reduction. Conclusion . Although reduction does not reduce the live birth rate, it does reduce gestation age of delivery and birth weight of newborn. This effect is more apparent when multiple gestation is reduced to singleton.