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... transmission cycle begins when, during a bite, the mosquito ingests mammalian blood infected with amastigote forms. Once installed in the digestive tract of the host, Leishmania passes through the process of differentiation, methacyclogenesis, and the new form of the parasite, promastigote, can be inject in mammalian blood again during a bite, thus completing the disease transmission cycle (Figure 4). Nanoparticle Technology: An alternative approach for Leishmaniasis Treatment http://dx.doi.org/10.5772/57283 ...