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Left: Schematic of the chrono-amperometric potential step protocol. Right: Significant stability improvement by the chrono-amperometric protocol with electrode renewal steps in comparison to steady-state amperometry signals for 5 mM glucose in 0.1 M phosphate buffered saline.
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Stability of hierarchical micro- and nanostructured platinum electrodes for non-enzymatic glucose sensors were investigated taking into account the two major aspects of stability. The first aspect, the loss of sensitivity due to poisoning by reaction products was significantly minimized by using a potential-step protocol during chronoamperometric a...
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... the constant potential measurement a potential of 0.45 V vs. Ag/AgCl (1.09 V vs. RHE) was used, as prior works of our group have shown that this potential delivers the best results in terms of sensitivity for non-enzymatic glucose measurement with our hierarchical micro-and nanostructure [4]. The potential step protocol was applied as shown in Fig. 1 (left). While the potential E meas is applied the glucose is detected but the electrode also gets poisoned over time. By applying a reduction potential E red the platinum oxide and the absorbed species on the surface of the micro-and nanostructured platinum is removed. Subsequently the platinum oxide layer is renewed by using the ...
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... the electrode also gets poisoned over time. By applying a reduction potential E red the platinum oxide and the absorbed species on the surface of the micro-and nanostructured platinum is removed. Subsequently the platinum oxide layer is renewed by using the oxidizing potential E ox so that the electrode is prepared for the next measurement step. Fig. 1 (right) shows the stability of the amperometric glucose detection with the steady-state potential in comparison to the chrono-amperometric protocol over a time period of 12 h. While for the constant potential the signal strength is constantly declining over time, the chrono-amperometric protocol shows a relatively constant signal with only a ...
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