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Ledebouria hyderabadensis M. V. Ramana, Prasanna & Venu, a new species allied to L. revoluta (L. f.) Jessop, is described and illustrated from Greater Hyderabad of Andhra Pradesh, India.
Citations
... Ledebouria hyderabadensis is a new species found in the city limits of Hyderabad, Telangana, India, in 2012 (Ramana, 2012). The existence of the plant Ledebouria hyderabadensis is not reported elsewhere in the state or India. ...
Ledebouria hyderabadensis is a new species found in the city limits of Hyderabad, Telangana, India, in 2012. Ethanolic extract of L. hyderabadensis bulbs was measured for its antioxidant and antihypertensive. Phytochemical investigation revealed that the plant contains glycosides, saponins, flavonoids, tannins, carbohydrates, amino acids. Acute toxicity studies performed according to OECD 423 guidelines, where a single dose of 5, 50, 300 and 1000 mg/kg of ethanolic extract of L. hyderabadensis bulbs administered to rats did not displayed any toxic symptoms. Therefore 1000 mg/kg is chosen as the therapeutic dose. The ethanolic extract of L. hyderabadensis bulbs exhibited the DPPH and NO free radical scavenging activity in dose dependent manner than ascorbic acid with IC50 value 54.08 µg/ml and 64.67 µg/ml. The L. hyderabadensis extract exhibited statistically significant (p < 0.05) ACE enzyme inhibition IC50 values (59.64µg/ml) when compared to the standard Captopril (IC50=24.67µg/ml). DOCA salt treatment at the 100 mg/kg, and 200 mg/kg doses, significantly reduced the Mean Systolic Blood Pressure (MSBP) (198.8&169.4) compared with the standard Nifedipine (132.6) and the negative control (122.6).
... The current center of diversity is the Limpopo, Mpumalanga, and KwaZulu-Natal regions of South Africa (Venter, 1993), with a secondary center in East Africa (Lebatha et al., 2006;Lebatha, 2004), both of which may simply reflect a geographic bias in our understanding of Ledebouriinae diversity. For example, throughout the distribution of the Ledebouriinae, studies continue to reveal undescribed diversity within the group (Howard, 2014;Ramana et al., 2012). Taxonomically, the group currently consists of Ledebouria Roth with two sections: Drimiopsis (Lindl. ...
The Ledebouriinae (Scilloideae, Asparagaceae) are a widespread group of bulbous geophytes found predominantly throughout seasonal climates in sub-Saharan Africa, with a handful of taxa in Madagascar, the Middle East, India, and Sri Lanka. Phylogenetic relationships within the group have been historically difficult to elucidate. Here, we provide the first phylogenomic perspective into the Ledebouriinae. Using the Angiosperms353 targeted enrichment probe set, we consistently recovered four major clades (i.e., two Ledebouria clades, Drimiopsis, and Resnova). The two Ledebouria clades closely align with geography, either consisting almost entirely of sub-Saharan African taxa (Ledebouria Clade A), or East African and non-African taxa (Ledebouria Clade B). Our results suggest that the Ledebouriinae likely underwent a rapid radiation leading to rampant incomplete lineage sorting. We additionally find evidence for potential historical hybridization between Drimiopsis and a subclade within Ledebouria Clade A.
... L. karnatakensis Punekar & Lakshmin. and L. hyderabadensis M.V. Ramana, P r a s a n n a & V e n u ( P u n e k a r a n d Lakshminarasimhan 2011, Ramana et al. 2012). ...
In this study 27 populations of Ledebouria revoluata (Asparagaceae) from different localities in the peninsular India were examined for stomatal frequency, stomatal index, stomatal cell size, epidermal cell frequency and epidermal cell size. The results showed that there were significant differences in different populations in terms of leaf shape, size and stomatal parameters. Leaves were amphistomatic and their length ranged from 4.0 – 33.7 cm. In majority of the populations, stomatal frequency was higher on abaxial side with maximum value (137.20/mm2 ) recorded in the population collected from the Shivaji University Campus, Kolhapur.
... In 2012, Ramana et. al., [7] reported a new taxon, Ledebouria hyderabadensis is recognized as the first collection from the Hyderabad city of Telangana state from India. L. hyderabadensis is being a new plant any kind of earlier reports are not available related to phytochemical analysis and antimicrobial activity and hence, this prompted us to look into its phytochemistry and biological activity. ...
Plants are good source for the bioactive compounds and are used as traditional medicines. Phytochemical investigation of plants emphasizes in traditional medicines has yielded various bioactive compounds with different pharmacological activities. In the Hyacinthaceae family, Ledebouria genus is the weakly evergreen bulbs. Ledebouria hyderabadensis is a new toxin exist in the Hyderabad city of Telangana state, India. In the present study, we have carried out isolation of homoisoflavone from the underground bulbs of L. hyderabadensis and phytochemical screening of crude extracts of bulbs of L. hyderabadensis. The methanol extract of underground bulbs and isolated compound were screened for antimicrobial activity. Both the methanol extract and isolated compound Scillascillin shows significant antimicrobial activity.
... Flowers 10 to 25, pinkish green; bract c. 2 mm long, lunate; pedicels 3-4 mm long; tepals oblong, c. 6 × 2 mm, connate at base, apex acute, pinkish purple with green veins, reflexed in mature flowers; filaments free or adnate to tepals, pink, c. 4 mm long; anthers oblong; ovary stipitate, shallowly but distinctly three-lobed; style c. 4 mm long, erect, pink; stigma penicillate. Capsule obovoid, c. 5 × 7 mm, membranous, uni-to bi-locular, rarely trilocular, with persistent perianth and staminal filaments; seeds one per locule, obovoid, 4 mm diameter, testa smooth, brownish (modified from Ramana et al. 2012). ...
... In recent years, these characters have been used to delimit two new species Ledebouria karnatakensisPunekar & Lakshmin. (2011) and Ledebouria hydrabadensis M.V.Ramana, Prasanna & Venu (Ramana et al. 2012). While revising Ledebouria from India based on ecological, morphological and molecular studies, we found it necessary to revisit the taxa critically. ...
We recognize four species of Ledebouria Roth (Hyacinthaceae: Hyacinthoideae) from India, namely Ledebouria revoluta (L.f.) Jessop, Ledebouria viridis S. Dutta & P. Harvey ex M.R. Almeida, Ledebouria karnatakensis Punekar & Lakshmin. and Ledebouria hyderabadensis M.V. Ramana et al. The name Ledebouria junnarensis S.S. Rahangdale & S.R. Rahangdale is a later superfluous name for L. viridis. Lectotypes are designated for Ledebouria hyacinthina Roth & Bernardia indica Wight. Scilla hohenackeri Fischer & Mayer, earlier enumerated from India, is known from Pakistan and Central Asia, and is therefore, excluded from this work. We describe all four species, with their synonymy and updated nomenclature.
... It is found mostly in areas of summer rainfall (there are a few winter rainfall species) in subtropical savannas and grasslands in the eastern and northeastern parts of southern Africa. [1] This is recognized as the first collection made of the new taxon Ledebouria hyderabadgensis, [2] exist in the Hyderabad city of Andhra Pradesh (AP), India. In spite of its presence in the city localities, the new taxon is confined to rocky habitats and is not very frequent. ...
Background:
Ledebouria is a genus of deciduous or weakly evergreen bulbs in the Hyacinthaceae family. This is recognized as the first collection made of the new taxon Ledebouria hyderabadensis, exist in the Hyderabad city of Andhra Pradesh, India.
Objective:
The goal of this work was to investigate the phytochemical constituents present in the new specifies and also to evaluate the cytotoxic properties of the extracts and pure compounds against human cancer cell lines.
Materials and Methods:
The anticancer activity was evaluated in in vitro mode by 3-(4,5-dimethylthiazol-2-yl)-2,5-diphenyltetrazolium bromide (MTT) test.
Results:
Phytochemical investigation of underground bulbs of indigenous, rare, and recently identified herb L. hyderabadensis yielded a bioactive homoisoflavanone, Scillascillin 1. The structure of the compound was established on the basis of various nuclear magnetic resonance and mass spectral data. The compound Scillascillin was isolated for the first time from L. hyderabadensis. In vitro anticancer activity, performed using MTT assay, showed compound 1 as significantly active against human cancer cell lines MCF-7 (breast cancer) and DU-145 (prostate cancer) with inhibitory concentration (IC)50 values 9.59 and 11.32 μg/ml respectively when compared with herb methanol extract (IC50 values 36.21 and 44.86 μg/ml respectively).
Ledebouria hyderabadensis M. V. Ramana, Prasanna & Venu is reported here as a new distributional record for Tamil Nadu. Detailed description and photographs are provided to facilitate easy identification.
