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Large protruding ulcerated beefy red nodule with adjacent pinhead to bean-sized multiple nevi are present in the right zygoma (A). A flat, ill-defined, rice grain-sized, eroded, dark brown-colored patch in the superior portion of nasal bridge, between the eyes (B).
Source publication
A 'collision' tumor refers to the existence of two different neoplasms within the same tumor. Sometimes, the term 'biphasic tumor' is also used. However, a 'collision' tumor is defined as the occurrence of two neoplasms within proximity of each other yet maintaining distinctly defined, separate boundaries. In contrast, a 'biphasic' tumor demonstrat...
Contexts in source publication
Context 1
... 57-year-old male presented at our hospital with an ul- cerated, beefy red nodule, with adjacent pinhead to bean-sized multiple nevi in the right zygoma (Fig. 1A). The pruritic, erythematous lesion had been present for a long time and the lesion was reported to have rapidly in- creased in size over the previous four weeks, prior to the hospital visit. Further examination revealed an ill-defined, rice grain-sized, eroding deep brown patch in the superior portion of the nasal bridge, between the eyes (Fig. ...
Context 2
... 57-year-old male presented at our hospital with an ul- cerated, beefy red nodule, with adjacent pinhead to bean-sized multiple nevi in the right zygoma (Fig. 1A). The pruritic, erythematous lesion had been present for a long time and the lesion was reported to have rapidly in- creased in size over the previous four weeks, prior to the hospital visit. Further examination revealed an ill-defined, rice grain-sized, eroding deep brown patch in the superior portion of the nasal bridge, between the eyes (Fig. ...
Citations
... 5,8 The sarcomatoid carcinoma can potentially be confused with a wide variety of tumors including squamous cell carcinoma, breast ductal carcinoma, other skin adnexal carcinomas, and a variety of other mixed tumors of the skin which is why staining is vital to a correct diagnosis. 5,8,[9][10][11][12][13] Metastases of cutaneous sarcomatoid carcinomas may consist predominantly or exclusively of the sarcomatous element, carcinomatous element, or both. 5,8 In our patient's case, the metastases to the lung and brain consisted predominantly of the sarcomatous population. ...
Sarcomatoid sweat gland carcinomas are rare among cutaneous cancers, with less than 20 cases described. A 54‐year‐old woman with sarcomatoid sweat gland carcinoma of the right upper extremity suffered extensive recurrence at 15 months, unresponsive to chemotherapy. There is no standard treatment or chemotherapy regimens for metastatic sweat gland carcinoma.
... A variety of histologic patterns (eg, squamous cell, clear cell, spindle cell differentiation, and melanocytes colonization) were observed in EPC tumor cells. 1,27,58,100 In literature, there is a frequency of 5% to 42% for squamous cell 1,105-109 and 6% to 67% for clear cell differentiation, 1,105-108 whereas melanocyte colonization is found in 3% to 21%. 1,106 In our meta-analysis, EPC tumor cells showed squamous cell differentiation in 25.0% and clear cell differentiation in 23.4% of the cases. ...
Background
The aim of the study is to analyze potential prognostic factors and to evaluate therapy strategies regarding clinical outcome in patients with eccrine porocarcinoma (EPC) of the head and neck.
Methods
One hundred and sixteen EPC cases from ninety studies and four authors' EPC cases were included in the meta‐analysis.
Results
At an average follow up of 20.48 months, the 3‐year overall survival and regional recurrence rate were 70.3% and 19.0%, respectively. Patients without surgical treatment had a significantly worse 3‐year overall survival. Mohs microscopic surgery led to significantly less occurrence of regional recurrences compared to wide excision. An ulcerating lesion, high mitotic activity, and lymphovascular invasion were significant prognostic factors.
Conclusion
Surgical resection is the cornerstone in the therapy of EPC and represents the therapeutic modality that offers the best chance of disease‐free survival. Due to the high probability of recurrence, close follow‐ups are strongly recommended.
