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Laboratory findings of patients with idiopathic nephrotic syndrome according to the therapeutic response to steroids

Laboratory findings of patients with idiopathic nephrotic syndrome according to the therapeutic response to steroids

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Background: Cytokines are functional class of tiny proteins and glycoprotein and fundamentally they are monomers that function as soluble mediators in an autocrine or paracrine manner. Cytokines are produced by a number of cell types, predominantly leukocytes, and their targets implicate both immune and non-immune cells. Material and methods: This...

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... Additionally, our findings supported those of Agrawal et al. [3] who discovered that uMCP-1 may separate kids with SRNS from kids with SSNS when the condition first manifests. Moreover, Angela [24] noticed that SRNS patients exhibited greater MCP-1 levels in their urine than SSNS patients did. (p < 0.001). ...
... Furthermore, numerous investigations found that individuals with active idiopathic nephrotic syndrome excreted significantly more MCP-1 in their urine than did patients in remission or controls Angela [24] and Mariani et al. [25]. ...
... Esto sugiere que la IL-8, producida en respuesta a infecciones virales, puede jugar un rol en el mecanismo no mediado por CD80 de la proteinuria. (17)(18)(19) También se ha informado MCD post infección por SARS-CoV2. En estos casos aislados se podría sugerir un mimetismo molecular entre la proteína de la espiga SARS-CoV2 y antígenos propios de podocitos, como un eventual mecanismo fisiopatológico. ...
... En estos casos aislados se podría sugerir un mimetismo molecular entre la proteína de la espiga SARS-CoV2 y antígenos propios de podocitos, como un eventual mecanismo fisiopatológico. (8)(9)(10)(11)(12)(13)(14)(15)(16)(17)(18) La paciente presentó COVID-19 leve el año anterior sin haber experimentado síntomas, lo que haría menos probable este mecanismo. ...