Invasive SCC of the esophagus showing normal squamous mucosa in the left upper corner of the picture (arrows). Nests of malignant cells with hyperchromatic and enlarged nuclei and forming keratin pearls are seen infiltrating into the lamina propria and muscularis in the middle and right side of the picture (arrowheads). Image courtesy of the University of Massachusetts Medical School, Department of Pathology.

Context in source publication

Context 1

... cell carcinoma is the most common histology seen in the esophagus ( Figure 4). Adenocarcinoma (Figure 5a and 5b) is next most common, but incidence is rising rapidly in the developed world. ...