Figure 4 - uploaded by Davide de biase
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Immunohistochemical analysis of the inflammatory infiltrate, skin, mouse. Inflammatory infiltrate showed a prevalence of CD3 þ (a) and CD4 þ (b) cells. Very few scattered CD8-positive lymphocytes were observed (arrows) (c). CD45/B220 and IL-17 (d, e) immune-labelled inflammatory cells. (f) Immunofluorescence showing intense immunoreactivity of mast cells for IgE antibody (arrows). Bars ¼ 100 lm.
Contexts in source publication
Context 1
... analysis was performed to further characterize the inflammatory lymphocyte infiltrates, showing a predominant CD3 þ CD4 þ leukocyte population with fewer of CD45/B220-and Il-17-immunolabelled cells. We rarely observed scat- tered, CD8-labelled lymphocytes (Figure 4(a) to (e)). Interestingly, immunofluorescence revealed the pres- ence of numerous IgE-bound mast cells among the inflammatory infiltrates in the dermis and, in marked lesions, around blood vessels of the underlying subcuta- neous muscle and adipose tissue (Figure 4(f)). ...
Context 2
... rarely observed scat- tered, CD8-labelled lymphocytes (Figure 4(a) to (e)). Interestingly, immunofluorescence revealed the pres- ence of numerous IgE-bound mast cells among the inflammatory infiltrates in the dermis and, in marked lesions, around blood vessels of the underlying subcuta- neous muscle and adipose tissue (Figure 4(f)). ...
