Figure 1 - uploaded by James Vernon Odom
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Images of rat eye showing miosis of the pupil before (control) and after intraperitoneal exposure to 300 μg/kg parathion. Scale (bar) at lower left of image represents 1 mm. Arrows on images highlight edges of pupil for greater 2 clarity. Images were captured via a CCD camera linked to a video capture software. Light intensity was 1.7 cd/m .
Source publication
The sensitivity of the eye"s reaction to a wide variety of chemicals/toxins and its role as a gauge for internal homeostasis (e.g., cardiovascular and neurophysiological imbalances) has been extensively researched via many scientific disciplines. New techniques and equipment are both harnessing and utilizing this information to define a modern appr...
Contexts in source publication
Context 1
... data derived for exposed animals was in relation to individual controls (i.e., control pupil diameter values were obtained for each animal prior to injection of parathion). For proper control purposes, a group of animals (n=7) was given 1ml corn oil I.P. to ensure lack of miotic effect of the vehicle (see Figure 1). Test animal pupils were monitored and recorded continually post-injection of parathion for a period of 60 minutes under very low light intensity conditions (1.7 cd/m 2 ). ...
Context 2
... occurred for only 1 of 5 animals tested at this dose. An example of the miotic effects of parathion is illustrated in the series of pictures in Figure 1, showing the response of the pupil to I.P. injection of 100µg/kg at various time points. Miosis of the pupil in this figure is clearly observed (highlighted by the arrows) and captured via the video imaging system applied in this study. ...
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