Images of pancreatitis. (A) PET/CT scan from October 2020 showing pancreatic swelling consistent with pancreatitis. (B) PET scan from October 2020 showing standardized uptake values of 6.6 to 8.1 in the pancreas. (C) T1-weighted magnetic resonance image of the abdomen acquired in the axial plane in December 2020. The pancreas overall appears smaller in diameter than that on PET/CT performed in October 2020 (A), consistent with resolving pancreatitis. (D), PET/CT scan from June 2021 showing near resolution of diffuse pancreatic swelling. (E) PET scan from June 2021 showing decreased pancreatic standardized uptake values (2.3-3.3). Asterisks indicate pancreatitis. CT = computed tomography, PET = positron emission tomography.

Images of pancreatitis. (A) PET/CT scan from October 2020 showing pancreatic swelling consistent with pancreatitis. (B) PET scan from October 2020 showing standardized uptake values of 6.6 to 8.1 in the pancreas. (C) T1-weighted magnetic resonance image of the abdomen acquired in the axial plane in December 2020. The pancreas overall appears smaller in diameter than that on PET/CT performed in October 2020 (A), consistent with resolving pancreatitis. (D), PET/CT scan from June 2021 showing near resolution of diffuse pancreatic swelling. (E) PET scan from June 2021 showing decreased pancreatic standardized uptake values (2.3-3.3). Asterisks indicate pancreatitis. CT = computed tomography, PET = positron emission tomography.

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Rationale: Immunoglobulin (Ig) G4-related disease (IgG4-RD) reportedly has a strong relationship with adult-onset asthma and periocular xanthogranuloma (AAPOX) and may be linked to sclerosing mucoepidermoid carcinoma (MEC). We present a rare case of IgG4-RD and AAPOX occurring in a patient with resected eosinophilic or oncocytic MEC. Patient conc...

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Context 1
... of the rheumatologic workup on October 27, 2020, showed an initially normal IgG4 level of 38.8 mg/dL (Table 1). A repeated PET/CT scan showed interval development of diffuse swelling of the pancreas (Fig. 3A) with increased tracer uptake consistent with pancreatitis ( Fig. 3B), a common finding in IgG4-RD. [8] Amylase and lipase levels were elevated at 130 and 68 mg/dL, respectively. The patient, however, did not have symptoms of ...
Context 2
... of the rheumatologic workup on October 27, 2020, showed an initially normal IgG4 level of 38.8 mg/dL (Table 1). A repeated PET/CT scan showed interval development of diffuse swelling of the pancreas (Fig. 3A) with increased tracer uptake consistent with pancreatitis ( Fig. 3B), a common finding in IgG4-RD. [8] Amylase and lipase levels were elevated at 130 and 68 mg/dL, respectively. The patient, however, did not have symptoms of ...
Context 3
... was started instead on an oral glucocorticoid regimen (prednisone) and methotrexate, which have proved useful for treating both IgG4-RD and AAPOX. [2,15] Subsequently, she noted substantial improvement in her symptoms. Additionally, abdominal magnetic resonance imaging performed 2 months after initiation of treatment showed resolving pancreatitis (Fig. 3C). A subsequent measurement of her IgG4 level in January 2021 was elevated without explanation (Table 1). Another PET/CT scan in June 2021 showed resolution of tracer-avid findings at the left parotid fossa, left pharyngeal region, and bilateral aspect of the neck. These images also showed mild to borderline residual uptake in the right ...
Context 4
... (Table 1). Another PET/CT scan in June 2021 showed resolution of tracer-avid findings at the left parotid fossa, left pharyngeal region, and bilateral aspect of the neck. These images also showed mild to borderline residual uptake in the right inguinal region, skin of the right thigh, and near resolution of diffuse pancreatic swelling ( Fig. 3D) with standardized uptake values of 2.3 to 3.3 (Fig. 3E), a decrease from prior values of 6.6 to ...
Context 5
... resolution of tracer-avid findings at the left parotid fossa, left pharyngeal region, and bilateral aspect of the neck. These images also showed mild to borderline residual uptake in the right inguinal region, skin of the right thigh, and near resolution of diffuse pancreatic swelling ( Fig. 3D) with standardized uptake values of 2.3 to 3.3 (Fig. 3E), a decrease from prior values of 6.6 to ...

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