Image of the primary tumor, an intraventricular atypical choroid plexus papilloma. T1-weighted axial image with contrast shows a homogeneously enhancing lesion in the fourth ventricle with contact to and impression on the left middle cerebellar peduncle (arrow).

Image of the primary tumor, an intraventricular atypical choroid plexus papilloma. T1-weighted axial image with contrast shows a homogeneously enhancing lesion in the fourth ventricle with contact to and impression on the left middle cerebellar peduncle (arrow).

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Background: Choroid plexus papillomas (CPPs) are infrequently encountered brain tumors with the majority originating in the ventricular system. Rarely, CPP occurs outside of the ventricles. Case description: We report the case of a recurrent CPP that initially originated within the fourth ventricle, though years later it recurred in the left mid...

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Choroid plexus tumours (CPTs) account for 2–5% of brain tumours in children. They can spread along the neuraxis and can recur after treatment. Little is known about the molecular mechanisms underlying their formation and only few high fidelity mouse models of p53-deficient malignant CPTs are available. We show here that c-MYC overexpression in the...