Image of a close-up nephron and its place in the kidney. Labels on the kidney crosssection show where unfiltered blood enters, filtered blood leaves, and urine exits. On the nephron, the glomerulus, tubule, and collecting duct are labeled along with where unfiltered blood enters, filtered blood exits, and urine exits. Image credit: National Institute of Diabetes and Digestive and Kidney Diseases, National Institutes of Health.

Image of a close-up nephron and its place in the kidney. Labels on the kidney crosssection show where unfiltered blood enters, filtered blood leaves, and urine exits. On the nephron, the glomerulus, tubule, and collecting duct are labeled along with where unfiltered blood enters, filtered blood exits, and urine exits. Image credit: National Institute of Diabetes and Digestive and Kidney Diseases, National Institutes of Health.

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Purpose: The purpose of this review is to describe computational models that have been developed for studying kidney function and howthese models may be adapted to study the eyes. Methods: We derive equations for modeling solute andwater transport across epithelial cell membranes in the kidney. These equations describe mass conservation, as well me...

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Context 1
... human kidney is populated by approximately a million nephrons; each rat kidney, by approximately 40,000 nephrons. An illustration of a kidney, together with a close-up image of a nephron and its surrounding blood vessels, can be found in Figure 1. ...