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Hyaluronic acid structure diagram and main cross-linking sites. GlcA = D-glucuronic acid; GlcNAc = N-acetyl-d-glucosamine.

Hyaluronic acid structure diagram and main cross-linking sites. GlcA = D-glucuronic acid; GlcNAc = N-acetyl-d-glucosamine.

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Hyaluronic acid (HA) is a polysaccharide found in the extracellular matrix of the epithelial, nervous, and connective tissues of vertebrates. It is widely used in the treatment of ocular surface diseases (OSDs), including dry eye, due to its high water-retaining capacity, viscoelasticity, and role as a signaling molecule in inflammation and wound h...

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