Figure - available from: Metabolic Brain Disease
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Homology of GLUT-1 & GLUT-3 in Human, Rat, and Mouse model systems. The complementary DNA sequences (CDs) of GLUT-1 & GLUT-3 in mice, rats, and humans were aligned. Based on the differences in alignment, the phylogenetic tree was created using the Clustal W tool
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Glioblastoma Multiforme (GBM) is an aggressive brain cancer affecting glial cells and is chemo- and radio-resistant. Glucose is considered the most vital energy source for cancer cell proliferation. During metabolism, hexose molecules will be transported into the cells via transmembrane proteins known as glucose transporter (GLUT). Among them, GLUT...
