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Histopathology of the left preauricular lesion. A: panoramic view showing numerous sebaceous glands, some miniaturized (arrows), and smooth muscle bundles (hematoxylin-eosin stain, 4x). B: abundant smooth muscle bundles embedded in the collagen bundles and surrounding the mature sebaceous glands (Masson's trichrome stain, 10x). C: abundant smooth muscle bundles in the collagen (yellow arrows); miniaturized sebaceous follicles (black arrows) (Masson's trichrome stain, 20x). D: smooth muscle bundles (arrows) surrounding a mature sebaceous gland (Masson's trichrome stain, 40x).
Source publication
Background:
Acquired smooth muscle hamartoma (ASMH) is a rare benign lesion characterized clinically by hyperpigmented plaques with hypertrichosis and some follicular papules. The main histologic finding is the presence of disorganized smooth muscle bundles in the dermis. Only 25 cases of ASMH have been reported in the literature.
Clinical case:...
Context in source publication
Context 1
... follicular outgrowths were observed in the follicular component, and numerous intermingled smooth muscle bundles in the external, mid, and deep dermis with collagen disruption and sebaceous glands surroundings. Masson's trichrome staining was positive, showing enhancement of muscle bundles in red over dermal collagen tissue in blue ( Figure 3). Based on the clinicopathologic correlation, acquired smooth muscle hamartoma with a sebaceous component was diagnosed. ...
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