Figure 3 - uploaded by Raaj Chandra
Content may be subject to copyright.
Histopathology of the appendix. The 10× objective (left) showed ulcerated appendiceal mucosa with underlying granulomatous inflammation comprising epithelioid and multinucleate histiocytes, and lymphocytes. The 20× objective (right) showed caseating granulomatous inflammation comprising central necrosis (arrowhead) surrounded by palisaded epithelioid histiocytes (solid arrowhead), including one multinucleate cell (arrow).
Source publication
Context in source publication
Context 1
... the inflamed appendix had focally nodular thickened wall. Microscopy revealed extensive mucosal ulceration and granulomas with some necrosis (Fig. 3). There were no mycobacteria identified with Ziehl-Neelsen or Wade-Fite stains. The tissue was sent for Mycobacterium tuberculosis and atypical mycobacterial polymerase chain reaction (PCR). No acid-fast bacilli were detected in the patient's sputum and intraperitoneal fluid. The mycobacterium culture was ...
Similar publications
Mucocele of the appendix is the accumulation of mucoid material in the appendiceal lumen. Although the terminology is imprecise, as it does not differentiate between the benign and malignant nature of the condition, preoperative recognition is imperative as spillage of the mucus during surgical handling can result in grave complications like pseudo...
Appendicitis of the appendicular stump is a rare surgical complication characterized by inflammation of the residual appendix. A past history of appendectomy and abdominal pain with nonspecific characteristics are frequent causes of delayed diagnosis, which may be associated with serious complications, namely, intra-abdominal abscesses, perforation...
Citations
... En la mayoría de los casos no hay síntomas ni signos clásicos que orienten hacia una apendicitis tuberculosa, y es el informe histopatológico el que conduce al diagnóstico 6 . Los hallazgos histopatológicos clásicos son necrosis de caseificación y células gigantes de Langhans 17 . ...
... The initial type is a chronic form characterized by abdominal pain, diarrhea, and occasional vomiting. This form is often mistaken for ileocecal TB [11]. The second type is an acute form with symptoms resembling surgical abdomen appendicitis, as observed in our patient [12]. ...
According to the World Health Organization (WHO), tuberculosis (TB) is the 13th cause of death worldwide and the second infectious killer after HIV. It is an endemic disease in Morocco. Isolated appendicular TB is an uncommon form of extrapulmonary TB. We report a case of a 26-year-old woman admitted for acute abdominal pain in the right iliac fossa with fever, vomiting, and diarrhea. Physical examination and abdominal ultrasound confirmed appendicitis. Surgery was performed and revealed on histopathological examination of the resected appendix the diagnosis of tubercular appendicitis. The patient was initiated on the conventional antitubercular regimen for six months and would be followed up appropriately. This case report highlights the importance of histopathological examination of appendicectomy specimens in order to diagnose rare diseases such as primary TB of the appendix.
Gastrointestinal tuberculosis is a rare extrapulmonary manifestation, it represents 3% of cases and mainly involves the ileocecal region; appendiceal involvement is rare. Tuberculous appendicitis can present as an acute condition indistinguishable from other causes of appendicitis and the diagnosis is generally made by histopathological finding, which delays treatment and can lead to complications. The postpartum period is at risk of a reactivation of tuberculosis, due to changes in the immune system that manifests as an immune reconstitution syndrome. We present the case of a postpartum patient admitted for septic shock secondary to perforated appendicitis, the pathology reported chronic granulomatous inflammation and subsequent confirmation by molecular technique of pulmonary tuberculosis.
