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Histopathology. (A) Hypertrophied myocardium with patchy interstitial fibrosis (black arrows; hematoxylin and eosin; Â10 magnification). (B) The same section of hypertrophied myocardium using a trichrome stain to highlight areas of fibrosis in blue (black arrows; Â10 magnification). (C) A close-up of interstitial fibrosis within the myocardium (hematoxylin and eosin; Â40 magnification).

Histopathology. (A) Hypertrophied myocardium with patchy interstitial fibrosis (black arrows; hematoxylin and eosin; Â10 magnification). (B) The same section of hypertrophied myocardium using a trichrome stain to highlight areas of fibrosis in blue (black arrows; Â10 magnification). (C) A close-up of interstitial fibrosis within the myocardium (hematoxylin and eosin; Â40 magnification).

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Figure 2 Two-dimensional TTE apical 4-chamber views in diastole (left)...
Figure 3 Computed tomography chest without contrast, axial image,...
Figure 4 Cardiac magnetic resonance delayed contrast enhanced images,...
Figure 5 Histopathology. (A) Hypertrophied myocardium with patchy...
Rapidly Progressive Primary Scleroderma Cardiomyopathy in a Young Adult Characterized by Multimodality Imaging
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  • May 2023
Highlights •Scleroderma-related heart disease is usually secondary to lung disease or PH. •Scleroderma rarely causes systolic HF in young patients or those without CAD. •A multimodality strategy should be used to characterize scleroderma cardiomyopathy.
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... days later, a right heart catheterization, coronary angiography, and endomyocardial biopy demonstrated angiographically normal coronary arteries, mild PH, normal cardiac filling pressures (RA pressure = 4 mm Hg; pulmonary capillary wedge pressure = 13 mm Hg), and normal cardiac output. Histopathologic results from the endomyocardial biopy showed myocardial hypertrophy with patchy interstitial fibrosis ( Figure 5 ...