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Actinic prurigo (AP) is a type of photodermatosis that primarily affects the Latin American mestizo population. Histologically, AP cheilitis exhibits acanthosis with spongiosis and vacuolation of the basal cell layer overlying a dense lymphocytic inflammatory infiltrate that forms well-defined lymphoid follicles. Toluidine blue is a thiazide, acido...
Context in source publication
Context 1
... lower lip involvement at the vermillion border is common in a high percentage of the affected individuals and maybe the only expression of the disease, when is commonly termed as AP cheilitis; in this location, it is characterized by edema, cracks, fissures, ulcers that are covered by serohematic crusts, erythema and areas of residual hyperpigmentation. that is associated with intense pruritus that extends to the adjacent skin. 1 Histologically, AP cheilitis exhibits acanthosis with spongiosis and vacuolation of the basal cell layer overlying a dense lymphocytic inflammatory infiltrate that forms well-defined lymphoid follicles (comprising B lymphocytes in the center and T lymphocytes at the periphery), macrophages, eosinophils, and mast cells ( Figure 1). 2 AP cheilitis affects 85% of patients and is the sole manifestation of the disease in 27% of those who are affected. ...
