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Basal cell carcinoma (BCC) is a frequent form of skin cancer, which usually affects people that have been exposed to the sunlight for longer periods of time. The cells of the lower part of the epidermis are called the basal cell layer. These cells constantly divide to form new cells to replace the squamous cells that wear off the skin's surface. As...
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Sinonasal mucosal melanoma (SNMM) is a rare tumor with a poor prognosis. This study aimed to assess the clinical and imaging features, progression, treatment, and possible prognostic factors of SNMM.
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Basal cell carcinoma (BCC) is the most frequent skin cancer and its location in the nasal pyramid poses treatment problems. The main issue is how large the resection margins should be. The article presents a retrospective study on patients with BCCs of the nose. Thirty-seven patients were included and the correlations between incomplete resections...
Citations
... The development of skin cancer in the head and neck region and especially in the nose area is one of the most common sites in 31.25% of the cases, due to the prolonged and unavoidable sun exposure (Dincă et al., 2019;Derebaślnlloǧlu and Özkaya, 2021). The two most frequent tumours that appear in this region are the basal cell carcinoma (BCC) and squamous cell carcinoma (SCC) (Uzun et al., 2015;Ciążyńska et al., 2021). ...
Nasal reconstruction after surgical excision of non-melanoma skin cancer defects can be a challeng- ing condition for every head and neck surgeon. There are certain technical difficulties that may arise from the tissue deficit and the area that a locoregional flap could cover. What is more, patients with a compromised medical history cannot always receive surgical manage- ment under general anaesthesia, limiting even more the defect reconstruction options. The aim of the present study is to present two patients that were treated under local anaesthesia for advanced basal cell carcinomas of the nose, with modifications of paramedian and hemi- nasal flaps that provided excellent surgical and aesthetic outcomes, despite the limits of the surgical modality.
... The onset and progression of BCC is mainly connected to the exposure of skin to solar ultraviolet (UV) radiations. Therefore, these tumors occur on the head and neck skin, mainly on the nose and face, mainly in adult men working outdoors, aged over 50 years old [14,15]. The studies in the last decades showed that the BCC incidence has increased by 10% per year and it is diagnosed more and more often in people aged less than 40 years old) [16,17]. ...
Basal cell carcinoma (BCC) is the most frequent skin cancer and its location in the nasal pyramid poses treatment problems. The main issue is how large the resection margins should be. The article presents a retrospective study on patients with BCCs of the nose. Thirty-seven patients were included and the correlations between incomplete resections and tumor dimensions, resection margins or histological sub-type were investigated. Of the 37 patients, only five had tumor-positive excision margins, but no correlation with the above-mentioned factors could be found. An overall tendency to over-resection was detected, contrary to the tendency depicted in the literature, but the incomplete resection rate (13.5%) is comparable with other reports. Further studies are needed, on a larger population in order to generate guidelines to better medical practice on this matter.
Please see our paper : 10.1093/ageing/afac053
INTRODUCTION: End-of-life (EOL) with Alzheimer’s Disease or Related Syndromes (ADRS) is characterized by burdensome symptoms that may lead to unfavorable EOL healthcare utilization trajectories (HUTs). We aimed to identify unfavorable HUTs and their individual and contextual determinants. METHODS: Nationwide cohort study of incident ADRS cases identified in 2012, who died before 12/31/2017, using administrative data. We used multidimensional clustering of last year of life HUTs, experts’ assessment to qualify unfavorable HUTs and multilevel models to identify their determinants. RESULTS: 62243 subjects had died before 12/31/2017. 29881 (46.8%) faced unfavorable HUTs: 55.2% of community-dwelling and 31.8% of nursing-home subjects. For both settings, individual factors were associated with unfavorable HUTs: e.g., cancer (aOR=2.28;95%CI=[2.12-2.46]) or early resuscitation use (aOR=4.68; 95%CI=[3.89-5.62]). Contextual factors and deprivation were significant for community-dwelling subjects. DISCUSSION: Unfavorable EOL HUTs were frequent, especially among community-dwelling subjects. The role of contextual factors entails policy implications.
