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![Histology of rectal adenocarcinoma in dogs. A-The rectal mucosa presents the neoplasm growth of atypical epithelial cells with nuclear anisocytosis, anisocariosis and hyperchromasia in tubular formation [Bar= 100 µm]. B-The connective tissue between the muscle layers present lymphatic vessels with neoplasm growth of tubular pattern epithelial cells [Bar= 100 µm].](publication/334755363/figure/fig1/AS:786187300114433@1564453067208/Histology-of-rectal-adenocarcinoma-in-dogs-A-The-rectal-mucosa-presents-the-neoplasm.png)
Histology of rectal adenocarcinoma in dogs. A-The rectal mucosa presents the neoplasm growth of atypical epithelial cells with nuclear anisocytosis, anisocariosis and hyperchromasia in tubular formation [Bar= 100 µm]. B-The connective tissue between the muscle layers present lymphatic vessels with neoplasm growth of tubular pattern epithelial cells [Bar= 100 µm].
Source publication
Background: Intestinal neoplasms are uncommon in dogs and adenocarcinoma is the main histological type found. This neoplasm presents slow growth and high capacity of causing metastasis. Histologically speaking, neoplasm cells can present solid, tubular, papillary arrangement and note amorphous extra-cellular material. Clinically observed tenesmus,...
Contexts in source publication
Context 1
... histology of the rectal tissue depicted epithelium with differentiated neoformation, mainly in the crypts, composed of atypical cells; nuclear anisocytosis, anisocariasis and hyperchromasia placed in small islands, cords or tubular formations (Figure 2A). Neoplasm growth was unorganized and of infiltrative character; it established itself in the sub-mucosa, in the inner muscular layer, in the lymphatic vessels of intermuscular connective tissues ( Figure 2B) and in the lumen of sub-mucosa capillaries. ...
Context 2
... histology of the rectal tissue depicted epithelium with differentiated neoformation, mainly in the crypts, composed of atypical cells; nuclear anisocytosis, anisocariasis and hyperchromasia placed in small islands, cords or tubular formations (Figure 2A). Neoplasm growth was unorganized and of infiltrative character; it established itself in the sub-mucosa, in the inner muscular layer, in the lymphatic vessels of intermuscular connective tissues ( Figure 2B) and in the lumen of sub-mucosa capillaries. Some areas presented mucosal pattern cells with Signal Ring morphology; besides, mitotic figures were frequent. ...
