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Purpose:
To identify the prevalence, types, and patterns of colonic polyps in a cohort of patients presenting to a tertiary care referral center in Sri Lanka.
Methods:
Endoscopy and pathology reports of a single unit from 2006 to 2013 were analyzed retrospectively. Spearman's correlation coefficient and chi-square test were used to identify corr...
Context in source publication
Context 1
... commonest neoplastic histological type was tubulov- illous adenoma (í µí± = 63, 33.5%) followed by tubular adenoma (í µí± = 46, 24.5%). The commonest nonneoplastic histology type was hyperplastic polyps (í µí± = 32, 17%) followed by normal mucosa (í µí± = 15, 8%) ( Table 2). There was no correla- tion between the age and gender with site or histology. ...
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Background/aims:
Sigmoidoscopy is performed in most medical centers to evaluate the distal colons of young adults presenting with hematochezia who are at risk of developing proximal lesions. Colonoscopies offer more complete evaluations but are associated with a higher incidence of complications and possible low yield.
Methods:
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Background
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Background
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Citations
... [15] The histological distribution of colorectal polyps in the present study has been found similar to other studies. [15][16][17][18] In our study, 7.5% of the polyps were associated with a synchronous adenocarcinoma in the colon. In contrast, Lash et al. [19] found only 1% of the polyps in their study to be associated with a synchronous malignancy. ...
... The incidence of HPs and SSAs was similar to those of various other studies. [15][16][17][18] However, a study from Italy by Buda et al. [17] gave a higher proportion of SSAs (10.8%) and TSAs formed 2.3% of all polyps in their study which was not seen in other studies. ...
... Similar values were also reported in other studies. [15][16][17][18]21,26] In our study, 77.4% of the HPs and 100% of all SSAs measured <1 cm in size. In the study by Tony et al., [16] all the HPs were <1 cm in size, and in the study by Buda et al., [17] 98.6% of the HPs were <1 cm in size and 96.4% of the SSAs were below 1 cm in size. ...
Background
The World Health Organization introduced the entities of sessile serrated adenoma and traditional serrated adenoma, and hyperplastic polyps (HPs) under the serrated lesions category in 2010. Indian studies on demographic, clinical, and histopathological characteristics of colorectal polyps, especially on serrated lesions, are limited. Our study aimed to study the morphology of the colorectal polyps and estimate the percentage of serrated lesions in the polyps studied.
Methodology
A cross-sectional hospital-based study was conducted on colorectal polyps received for routine histopathological examination from July 2013 to August 2015. The polyps were classified according to the WHO 2010 colon and rectum tumors classification. Data were compiled and analyzed using IBM SPSS statistics version 20.0. The interpretation was done in frequencies and percentages.
Results
We studied a total of 200 colorectal polyps. The polyps were mostly seen in the descending colon (41%). Histologically, the majority of the colorectal polyps were adenomatous in nature (59%). The serrated lesions accounted for 29% of all colorectal polyps. The polyps were mostly seen in patients who were more than 40 years old.
Conclusion
Adenomas were the most prevalent type of colorectal polyps, seen more in males, at a higher age, and distally located. Serrated lesions predominantly included HPs, mostly <1 cm in size.
... 11 Similar to the study done by Jain et al we also found a male preponderance among adenomatous polyp with most of the patients being more than 60 years of age. 11,12 The results from many studies highlight that the profile of colonic polyps differs from one region to another. Multiple factors such as ethnicity, environmental factors, and variations in pathology reporting play a role for this variability. ...
Background: Colonic polyps are the abnormal growths from the colonic mucosa, usually benign but there is a definite though a small risk for cancerous transformation. Scarce data about this condition is available from Northern India. In this study we aimed to determine the prevalence of colonic polyps in patients undergoing colonoscopy for various health indications. In addition, we studied the various characteristics of these polyps including the histological classification Methods: In this observational cross-sectional study we included adult patients (≥18 years) who underwent colonoscopy from July 2016 to June 2018 at a tertiary care hospital setting in New Delhi, India. The socio-demographic variables were ascertained for all patients. Data about indication of colonoscopy, the findings on colonoscopy, finding regarding the colonic polyps (type, number, size, location and histological type) was collected. Results: We found a total of 246 patients to have colonic polyps and total number of polyps found was 369.The median age of the patients was 56 years (IQR 44-68). Majority of the patients with polyps (74.8%) were males. Polyps were most commonly seen in left colon (35.36%). Histologically, most common type was adenomatous polyps 58.9% (Tubular adenoma in 44% and tubule-villous adenoma in 8%). Hyperplastic polyps were noted in 22% followed by inflammatory polyps in 14% polyps. Adenocarcinoma was reported in 2 polyps (0.8%). Conclusions: Prevalence of colorectal polyps in our study is lower compared to most of the western countries. On histology majority of polyps were adenomatous.
... In the descending order of frequency, it is the rectum, sigmoid colon, transverse colon, descending colon, ascending colon, and the cecum. These findings are similar to observations in South Asia [68] and Iran. [69] However, it differs from another study in Iran in which the sigmoid colon and the descending colon were found to be the commonest sites for polyps. ...
Evaluation of colorectal pathologies by colonoscopy is increasingly reported from different centers across Nigeria. However, a comprehensive review of current colonoscopy practice across the country is yet to be documented. To report on colonoscopy practice, the detection rate, site(s), and geographic distribution of colorectal polyps in Nigeria, a systematic search was performed according to the Preferred Reporting Items for Systematic Reviews and Meta-Analyses statement. The search databases comprised MEDLINE, African Journal Online, and Google Scholar. The eligibility criteria included publications on flexible lower gastrointestinal endoscopies (LGIEs) performed on Nigerian population over a 20-year period from January 2002 to 2022. Relevant data on study characteristics, demographics of study patients, indication(s), complications of polypectomy, quality metrics for colonoscopy, polyp morphology size, location, and histopathology were extracted and analyzed. Twenty-one observational studies were included comprising 5821 patients who underwent LGIE with an age range of 2-101 years and an M: F of 1.8:1. The polyp detection rate (PDR) was 8.5% in NorthWest Nigeria, and the mean value ranged from 11.3% [95% confidence interval (CI) 7.0-15.6] in SouthWest Nigeria to 38.0% (95% CI 165.3-241.3) in South-South Nigeria. The rectosigmoid segment had the highest frequency of polyps [43% (358/828)], and adenomatous, inflammatory, hyperplastic, and malignant polyps were the frequent histology reported: 221 (26.7%), 174 (21.0%), 38 (4.6%), and 13(1.6%), respectively. Summarily, a large disparity exists in PDR among endoscopists in Nigeria. The training of Nigerian endoscopists on techniques to enhance caecal intubation rate, polyp detection, and comprehensive documentation of quality metrics in colonoscopy studies are recommended.
... Showing Dysplasia with relation to number of Colonic polyp.Albasri et al and Wickramasinghe et al studies showed that the commonest histolopathological type of polyp were tubulovillous adenoma (33.5%) followed by tubular adenoma (24.5%).9,15,29 Majority of cases in our study most polyp showed no dysplasia (94.64%) followed by 5.36% of polyp showing high grade dysplasia in form of nuclear stratification and broadening of nuclei. ...
Colorectal polyps are unusual growths of epithelial tissue projecting from the mucosaof the large bowel. This study aimed to evaluate the frequency of histological pattern of polyp among colorectal polypectomy specimen concerning age, sex, size, and site and histopathological features and associated dysplasia.
The study was done in the Pathology department in collaboration with the Gastroenterology Department on 115 patients. Biopsy was processed and histopathological features were studied with presence or absence of dysplasia.
Most patients had constipation (40.87%) followed by rectal bleeding (40.00%) followed by pain abdomen and anemia. Male patients were 76(66.08%) followed by 39(33.91%) female patients. Among male patients most are of age range of 50-59yr (18.42%) and in females were of age range of 60-69yr. (25.64%). Grossly most polyp are of pedunculated shape (74.78%) followed by ulcerated type (13.04%) and least was of sessile appearance (12.17%). Most polyp were found in left side (descending colon: 40.87%) followed by rectum, ascending colon, sigmoid colon and transverse colon with least with caecum. Most Polyps size < 1 cm (90.40%) followed by size of polyp > 1 cm (9.60%). Regarding the histopathological evaluation of polyp we have reported tubular adenoma (53.91%) followed by hyperplastic polyp (19.13%) followed by tubulovillous adenoma (13.04%). Most of the polyp showed no dysplasia (94.64%) and dysplasia if seen both in tubular adenoma and tubulovillous adenoma.
Colonoscopy is the most important tool in the detection of colonic polyp because of premalignant nature.
... Điều đó có nghĩa tỷ lệ Polyp ĐTT ở Việt Nam phải cao hơn tỷ lệ mắc ung thư ĐTT. Trong khi đó, một số nghiên cứu ở châu Á cho thấy tỷ lệ polyp ĐTT khá thấp: Wickramasinghe và cs [3], tỷ lệ polyp trên 100.000 dân ở Ấn Độ và Sri Lanka mắc polyp khoảng 2 người; Thái Lan là trên 100.000 dân. Tuy nhiên, nghiên cứu của Jayadevan và cs ở miền Nam Ấn Độ thì có 1 trong 6 người >40 tuổi có 1 polyp [4]. ...
... Số người chỉ có 1 polyp là 41 (36,3%); 2 polyp là 41 (36,3%), 3 polyp 24 (21,2%) và 7 người có từ 4 đến 100 (6,2%) polyp; số polyp trung bình cho 1 bệnh nhân là 2. Nếu so số bệnh nhân chỉ có 1 polyp đơn độc thì nghiên cứu của chúng tôi thấp hơn các nghiên cứu trong và ngoài nước: Nghiên cứu của Thái Thị Hồng Nhung và cs, polyp đơn độc 60,3%; Choe ở Hàn Quốc là 62,2% [5]; Wickramasinghe và cs ở Sri Lanka 81,6% [3]. ...
... Các polyp ít có khả năng ung thư hóa là các polyp tăng sản chiếm 38,9%. Trong khi đó, nghiên cứu của Wickramasinghe và cs [3], u lành tính chiếm 91,5% cao hơn nhiều nghiên cứu của chúng tôi (61,1%). ...
Mục tiêu: Dùng nội soi để tầm soát, chẩn đoán và điều trị polyp đại trực tràng (ĐTT) nhằm góp phần giảm thiểu tỷ lệ ung thư ĐTT cũng như điều trị cho bệnh nhân có polyp ĐTT lành tính. Đối tượng: Các bệnh nhân có triệu chứng của đường tiêu hóa dưới. Phương pháp: Tiến cứu, mô tả cắt ngang tại bệnh viện Nhật Tân, An Giang trong 1 năm (từ 10/2020 đến 9/2021). Kết quả: 440 bệnh nhân được nội soi và phát hiện 113 bệnh nhân có polyp, tỷ lệ 25,7%. Bệnh nhân có xuất huyết tiêu hóa dưới đến nội soi ĐTT chiếm tỷ lệ 39,3% so với không xuất huyết 16,4%, p<0,05 với OR=3,3 (KTC95%: 2,1-5,1). Thời gian xuất hiện triệu chứng ở người có polyp đến nội soi ĐTT sớm <6 tháng chiếm 67,6% so với người không có 32,4%, p<0,05, với OR=0,13 (KTC95%, 0,06-0,30). Số bệnh nhân có 1 polyp đơn độc là 41 (36,3%), các bệnh nhân khác có >2 polyp, bình quân 1 bệnh nhân có 2 polyp. Vị trí của polyp: 7 (6,2%) bệnh nhân có nhiều polyp rải khắp ĐTT, 36 (31,9%) ở đại tràng phải và 70 (61,9%) ở đại tràng trái. Có 12 bệnh nhân chẩn đoán qua nội soi có nguy cơ ác tính 12/18 chiếm 66,7% so với chẩn đoán giải phẫu bệnh là 57/95 bệnh nhân chiếm 60,0%, p> 0,05. Kết quả chẩn đoán polyp qua nội soi cho thấy khi so sánh với nghiệm pháp “chuẩn vàng” là giải phẫu bệnh lý, thì nội soi PĐTT chỉ đạt giá trị độ nhạy rất thấp (17,4%) và giá trị dự báo âm tính là 40%. Kết luận: Bệnh nhân có polyp thường đến nội soi sớm hơn với triệu chứng xuất huyết tiêu hóa. Chẩn đoán qua nội soi ĐTT dễ bỏ sót các polyp có nguy cơ ác tính và giải phẫu bệnh luôn là tiêu chuẩn vàng trong chẩn đoán polyp ĐTT.
... Comparable to our finding Kumar et al 12 had 85 % of the cases below 20years. In contrast, majority of cases were in the age group of >60 years in studies conducted by Jainet al and Wickramasinghe et al. 14,15 In the present study male (64.8%) preponderance was observed similar to other studies. 11 in which adult population was the predominant population. ...
... 11 in which adult population was the predominant population. 11,[14][15][16] The discrepancies in the distribution of lesions among these studies are likely due to differences in the predominant age group involved in the study. ...
Introduction: Gastrointestinal polyps are commonly encountered in the colorectal region. They can be non-neoplastic or neoplastic. Neoplastic polyps include adenomas which are clinically important because of their premalignant nature. The study was carried out to analyze the histomorphological spectrum of polyps; in our institution with special emphasis on adenomatous polyps.
Material and methods: This is a retrospective study done from January 2015 to December 2019 in the Department of Pathology, Dhulikhel Hospital - Kathmandu University Hospital (DH - KUH). Relevant clinical data of the patients were obtained from the histopathological records of the patient from the pathology department and biopsies stained with Haematoxylin and Eosin were studied under the light microscope.
Results: A total of 168 cases of polyp were studied from 125 patients. The most common indication for colonoscopy in patients with polyp was per rectal bleeding. The age of the patient ranged from 2 to 83 years. The rectum was the commonest location. 106(63.1%) of polyps were non-neoplastic and 6(36.9%) of polyps were neoplastic. Juvenile polyp(71;42.3%) was the commonest polyp. Tubular adenoma(55;32.7%) was the commonest neoplastic polyp. The
maximum number of neoplastic polyps were seen in the age group of 51-60years (11;29.7%). Male predominance was seen in neoplastic as well as a non-neoplastic polyp. High grade adenoma(4;6.7%) was more commonly seen in adenomatous polyp >2cm(3;75%) followed by 1-2cm(1;25%) and none in
... Other South Indian studies also showed similar results as in study done by Jain M et al 4 in Tamil Nadu ,most common polyp type was adenomatous (48.9 %) followed by hyperplastic (23.7%) and similarly another study done in Kerela by Tony J et al 3 had still higher number of adenomatous polyps (79.8%) and they also 1241 showed that amongst adenomatous polyps subtypes tubular was most common variety,followed by tubulovillous (24%) which is in concordance with the present study. However Wickramasinghe et al 11 found tubulovillous polyps were the commonest thus suggesting that polyp profile may vary differs in different regions owing to ethnicity,variations in pathology reporting and other environmental factors. ...
... Studies have been showed that approximately two-third of patients had solitary polyps, and advanced age is associated with detecting larger polyps (Lowenfels et al., 2011;Silva et al., 2014;Solakoğlu et al., 2014) Of the 1,106 polyps, adenomatous polyps were the most prevalent types, followed by mucosal tags/polyps, hyperplastic and serrated polyps, inflammatory polyps, hamartomatous, and malignant lesions. Frequency of adenomatous polyps in selected Iranian studies ranged between 61% and 90% (Mirzaie et al., 2012;Darvish et al., 2013;Iravani et al., 2014;Delavari et al., 2014;Hajmanoochehri et al., 2014;Geramizadeh and Keshtkar-Jahromi, 2013), and in some other countries varies between 41% and 61% (Zhou et al., 2017;Kefeli et al., 2014;Wickramasinghe et al., 2014;Valarini et al., 2011). It seems that in some of the mentioned studies in Iran, due to over-diagnosis of non-neoplastic polyps under Most polyps, including adenomas, located in the left colon, especially rectosigmoid. ...
... In a study at Hazrat Rasul Akram Hospital., as a pure group it accounts for 4.8% of all polyps, but in another review and as a combined class with inflammatory polyps this group constitutes 16% to 31% of all colonic polyps (Mirzaie et al., 2012). In series from other countries, this group accounts for 17% to 50% of all colonic polyps (Zhou et al., 2017;Kefeli et al., 2014;Wickramasinghe et al., 2014;Valarini et al., 2011). ...
... In Iranian studies, this group accounts for 0.3% to 2.1% of all polyps (Mirzaie et al., 2012;Iravani et al., 2014;Delavari et al., 2014;Hajmanoochehri et al., 2014;Geramizadeh and Keshtkar-Jahromi, 2013), and in other countries, this group constitutes 2% to 17% of all colonic polyps (Zhou et al., 2017;Kefeli et al., 2014;Wickramasinghe et al., 2014;Valarini et al., 2011). It seems that either these types of colonic polyps in Iran are not as common as western countries, or they remain undetected and misclassified as other polyps especially hyperplastic ones. ...
Aim:
This study was designed to report epidemiologic findings of polyps in Iranian patients, and predict histology of polyp regarding to demographic and colonoscopic findings.
Background:
Classification of colorectal polyps had been revised in the past two decades and there is a need for polyp categorization in the Iranian Health System.
Patients and methods:
In this retrospective study, the medical records of patients with colonoscopic diagnosis of polyp in pathology departments of SBMU affiliated teaching hospitals were reviewed. Patient's slides evaluated and demographics findings were assessed. The anatomical location, macroscopic appearance including size and histological assessment of all polyps were recorded.
Results:
From total number of 1106 polyps (detected in 862 patients), adenomatous polyps (638 [57.7%]) were the most prevalent findings, followed by colon mucosal tag (184[16.6%]), hyperplastic and serrated polyps (122[11%]), inflammatory polyps (110[9.9%]), hamartomatous (21[1.9%]), and malignant lesions (13[1.2%]). Multivariate logistic regression showed age (each one year increasing age; odds ratio [OR] = 1.026, 95%confidence interval [CI] = 1.016-1.036, p < 0.0001), location of polyp (right colon; OR = 1.905, 95%CI = 1.366-2.656, p < 0.0001), and polyp size of 5-10 mm (OR = 1.662, 95%CI = 1.214-2.276, p = 0.002), and polyp size of >10 mm (OR = 2.778, 95%CI = 1.750-4.411, p< 0.0001) were independently associated with neoplastic polyps. Also, polyp size of >10 mm (OR= 2.613, 95%CI= 1.083-6.307, p=0.033), tubulovillous pattern of polyp (OR= 3.508, 95%CI= 1.666-7.387, p=0.001) and villous pattern of polyp (OR= 10.444, 95%CI= 4.211-25.905, p.
... The prevalence of diverticulosis is very low in India and in western society its prevalence increases with age from 5% by age of 40 years to 65% at 80 years of age [5]. Colonic polyp occurs in younger population and its prevalence found to be about 2% in India [6]. Development of flexible sigmoidoscopy and colonoscopy has revolutionized the overall management of colonic diseases that is because colonoscopy is highly sensitive and specific procedure and is relatively safe with lower incidence of serious complications [7,8]. ...
Introduction: Colonoscopy, for any suspected colonic disease is the first line of investigation. The spectrum of colonic diseases varies from benign to malignant lesions, of which the incidence and mortality differ across the world due to differences in risk factors. Colonoscopy is carried out for diagnostic and/or therapeutic purposes. Materials and Methods: It was a hospital based cross sectional study conducted in Dr. Shankarrao Chavan Govt. Medical College, Nanded, during study period of May 2016 to December 2017 on 104 patients presented with clinical features of large bowel diseases. Results: The mean age of the patients was 45.59 ± 18.46 years (range 5 – 95). Males constituted 64.4% patients while females were 35.6%. On colonoscopy most common suspected diagnosis was carcinoma rectum (45.3%), followed by inflammatory bowel disease (26.7%) and rectal polyp (12%). Most of the lesions were found overall in rectum (49.5 %) followed by sigmoid colon (16.8%) and caecum (12.6%). Conclusion: Colonoscopy is a safe and simple procedure helps in locating various lesions in the entire colon and confirming the diagnosis by histopathology. Colonoscopy helps not only in the diagnosis but also in the treatment and follow up of the patient especially in the colonic diseases like colonic cancer and inflammatory bowel diseases.
... Wickramasinghe et al. from Srilanka reported 158 patients (median age 56.5 years, male:female 2:1) with CP. 76% of the polyps were left sided, and tubulovillous polyps were the commonest. [7] The results from these studies highlight that the profile of CP differs from one region to another. This could be due to multiple factors such as ethnicity, environmental factors, and variations in pathology reporting. ...
Background: The histological nature of polyps by site prevalence and size is unclear. Aim: To determine the prevalence of polyps in patients undergoing routine lower gastrointestinal (LGI) endoscopy and identify the histological types and their characteristics by age, location and size. Materials and Methods: For this retrospective study, patients undergoing ileocolonoscopy or sigmoidoscopy between 2014 and 2016 were included. Data on age, gender, test indication, site and size of polyps and histology type were collected. Results: Two hundred and ninety (12.7%) of 2303 patients who underwent LGI endoscopy had colonic polyps (n= 317; single in 272 patients). The median age was 61.1 years (range 5-99 years) and 223 (76.4%) were men. Polyps were rare
