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Fungal keratitis, an infective disease of the cornea, represents a serious diagnostic and therapeutic problem that, if not recognized on time, could lead to irreversible eye damage. Herein we report a case of fungal keratitis due to Fusarium spp. infection. The 60-year-old man was admitted to our clinic due to an atraumatic acute onset of the disea...
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Context 1
... corneal scraping was done and material was sent for microbiological examinations that were performed using standard methodology. After 5 days, filamentous colonies were formed on media incubated on 26 °C (Figure 1). Microscopic examination of these colonies demonstrated characteristic sporulation which indicated Fusarium species (septate hyphae with formation of numerous hyaline, multiseptated, fusiform to sickle shaped macroconidia) (Figure 2). ...
Citations
... The patient was initially treated withfluconazole, but the course was marked by a significant worsening of his keratitis, manifesting as a full-thickness total corneal infiltrate and a more intense reaction of the anterior chamber of eye l. Ultimately, the patient had to undergo evisceration to manage the situation [18] ...
Fungal keratitis is a destructive ocular infection, representing a serious diagnostic and therapeutic problem, difficult to treat and with poor results. It can cause irreversible damage. Keratomycoses are rare and may be under-diagnosed. Direct microscopic examination and culture are essential for early specific diagnosis and must be taken into consideration to establish the most effective treatment and avoid serious complications. The pathogenesis of this infection is based on three factors: colonization, tissue damage and immunosuppression. We report 2 cases of Fusarium oxysporum keratomycosis treated with amphotericin B. The diagnosis of corneal abscess was made after ophthalmological examination in 2 adult males with no previous ophthalmological history, referred to the Omar Drissi hospital in Fez for decreased visual acuity, photophobia, redness and intense pain in the right/left eye. Corneal scrapings were taken for microbiological analysis, and after initial mycological results, local and systemic antifungal treatment was initiated with amphotericin B and natamycin eye drops. The evolution was marked by a corneal perforation with a tenon patch graft for the first patient, and healing for the 2nd
