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G-band chromosome preparation shows a normal chromosome 21 (arrow) and an aberrant chromosome 21 [inv(21)].  

G-band chromosome preparation shows a normal chromosome 21 (arrow) and an aberrant chromosome 21 [inv(21)].  

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... of 7.79 cm and a femur length of 6.27 cm equivalent to 33 weeks, and in- ternal organs were unremarkable. Magnetic resonance imaging (MRI) revealed normal brain volume and no structural abnormalities. Elective amniocentesis was performed due to maternal anxiety. Cytogenetic analysis of cultured amniocytes showed an aberrant chromosome 21 ( Fig. 1). Karyotyping of the parental blood lymphocytes identified the same aberrant chromosome 21 in the father. The maternal karyotype was normal. Standard Ag-nucleolus organizer region (NOR) staining showed two NORs on the aberrant chromosome 21 with one NOR on the region of the short arm and the other ectopic NOR on the terminal region of ...

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