Fig 3 - available from: Diagnostic Pathology
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Source publication
Background:
Ischemic fasciitis is a distinctive pseudosarcomatous entity with a marked predilection for elderly and physically debilitated or immobilized patients. The etiology of these lesions is unknown but felt to be related to ischemic vascular events.
Case presentation:
Herein, we report for the first time, two cytogenetic translocations, t...
Context in source publication
Context 1
... cytogenetic analysis of the sample showed an abnormal karyotype with a translocation between chromosome 1 and 2, and a translocation between chromosome 7 and 19. A total of 20 cells were karyo- typed and 5 cells (25%) contained cytogenetic abnormal- ities. A full karyotype present was as follows: 46,XX,t(1;2)(p36.1;q23) [3]/46,idem,t(7;19)(q32;q13.3) [2]/ 46,XX[12]/nonclonal [3] (Fig. ...
Citations
Ischemic fasciitis is a benign fibroblastic-myofibroblastic proliferation also known as atypical decubital fibroplasia.
This chapter covers a large number of benign entities grouped together for convenience under the broad categories of fibrous, fibrohistiocytic, and myofibroblastic lesions. Fibrous lesions generally demonstrate a conspicuous increase in collagen production and varying numbers of fibroblastic spindle cells. “Fibrohistiocytic,” a somewhat enigmatic term, is a general descriptor for tumors containing a combination of spindle cells of putative fibroblastic, myofibroblastic, and/or primitive mesenchymal cell origin and histiocytes (bone marrow-derived tissue macrophages and dendritic cells). Myofibroblastic lesions are composed of spindle cells with combined features of smooth muscle cells and fibroblasts.
