Figure - available from: Nanomaterials
This content is subject to copyright.
Fourier transform infrared spectroscopy (FTIR) spectra of Fe3O4 NPs and NH2-Fe3O4 NPs (A), the X-ray diffraction (XRD) pattern of NH2-Fe3O4 NPs (B) and the vibrating sample magnetometer (VSM) of NH2-Fe3O4 NPs (C).
Source publication
A new electrochemical sensor for nanomolar rutin detection based on amine-functionalized Fe 3 O 4 nanoparticles and electrochemically reduced graphene oxide nanocomposite modified glassy carbon electrode (NH 2-Fe 3 O 4 NPs-ErGO/GCE) was fabricated through a simple method, and the X-ray diffraction (XRD), Fourier transform infrared spectroscopy (FTI...
Similar publications
In this work, a simple, disposable electrochemical sensor based on functionalized Multiwalled carbon nanotubes (f-MWCNT) modified screen printed carbon electrode (SPCE) was developed, which was used for the determination of catechol (CT). Transmission electron microscopy (TEM), Fourier transform infrared spectroscopy (FT-IR), Raman spectroscopy was...
Citations
... Extensive research has focused on exploring the potential therapeutic benefits of rutin in the treatment and prevention of various diseases, including cardiovascular disorders, diabetes, and neurodegenerative conditions [25][26][27][28][29]. The precise and sensitive detection of rutin in different sample matrices, such as food, pharmaceuticals, and biological fluids, holds significant importance for quality control, pharmacokinetic studies, and clinical applications [30][31][32]. Electrochemical sensing techniques, which exploit the redox properties of rutin, have emerged as a popular choice for rutin determination across diverse sample types, owing to their simplicity, cost-effectiveness, high sensitivity, and rapid response [33,34]. This paper presents the synthesis and characterization of ZnO-GO nanocomposites through a straightforward and efficient hydrothermal method, along with their application for the electrochemical detection of rutin. ...
In this study, a novel nanocomposite of graphene oxide-zinc oxide-manganese (GO-ZnO-M) was successfully synthesized using a modified Hummers method and hydrothermal technique. Enhanced electrochemical performance was observed in the GO-ZnO-M nanocomposite when utilized as an electrode material for the detection of rutin, a flavonoid known for its significant health benefits. The GO-ZnO-M modified electrode demonstrated excellent sensitivity, selectivity, reproducibility, and stability during rutin detection. Furthermore, the sensor exhibited a wide linear detection range and a low detection limit. The practical applicability of the GO-ZnO-M/ GCE sensor was assessed by detecting rutin in pharmaceutical tablet samples, yielding satisfactory results. This study highlights the potential of GO-ZnO-M nanocomposites as promising materials for the electrochemical detection of rutin and other biologically significant compounds.
... But the long complex process and limited range of detection restricted the use of these traditional techniques. Nowadays, the electrochemical biosensors have gained the attention of the scientific community because of its magnificent range of detection, facile processing, and high selectivity and sensitivity [21][22][23][24][25][26][27]. With this, various methods are used to immobilize the enzymes onto the electrode's surface by adsorption, covalent, and intermediate molecular linkage, which affects the sensing ability of the electrochemical sensors. ...
Here, we envisage the development of the rapid, reliable, and facile electrochemical sensor for the primary detection of xanthine (Xn) which is significant for the food quality measurement , based on the silver-doped molybdenum disulfide (Ag@MoS 2) nanosheets. The structural and compositional properties of the prepared samples were tested through X-ray diffraction (XRD), Fourier transform infrared (FT-IR) spectroscopy, and X-ray photon spectroscopy (XPS). The two-dimensional (2D) MoS 2 nanosheets provide the large surface area for the sensing applications and the silver ions help in the enhanced electrochemical response. The fabricated enzymatic biosensor exhibits magnificent cyclic stability with a limit of detection of 27 nM. Also, the sensor was tested for rapid, reproducible, specific, and regenerable up to 10 cycles and has a shelf life of 2 weeks. The outcomes of this study suggest that the proposed matrix could be employed for the fabrication of devices for early detection of xanthine.
... To synthesize graphene oxide (GO), the modified Hummers method was utilized, and the procedure was described in our previous report [44]. MnS/Co 3 S 4 nanohybrids were synthesized according to the procedure reported in our previously work [42]. ...
... Flavonols are electrochemical compounds that are well-suited for detection using electrochemical methods due to the presence of a hydroxyl group that enables their oxidation or reduction in the presence of different electrodes [103]. ...
... Some materials have been used and altered to detect rutin through electrochemical means. These materials include glassy carbon electrodes, glassy carbon electrodes modified with graphene oxide, glassy carbon electrodes modified with amine-functionalized Fe 3 O 4 nanoparticles [103] and pyridine-modified carbon paste electrodes, which have a detection limit of 3.58 × 10 −7 M [105]. ...
In vitro and in vivo studies have demonstrated the bioactivity of rutin, a dietary flavonol naturally found in several plant species. Despite widespread knowledge of its numerous health benefits, such as anti-inflammatory, antidiabetic, hepatoprotective and cardiovascular effects, industrial use of rutin is still limited due to its low solubility in aqueous media, the characteristic bitter and astringent taste of phenolic compounds and its susceptibility to degradation during processing. To expand its applications and preserve its biological activity, novel encapsulation systems have been developed. This review presents updated research on the extraction sources and methodologies of rutin from fruit and vegetable products commonly found in a regular diet and grown using family farming approaches. Additionally, this review covers quantitative analysis techniques, encapsulation methods utilizing nanoparticles, colloidal and heterodisperse systems, as well as industrial applications of rutin.
... RGO is obtained by chemical reduction or electrochemical reduction. In our previous work, we have successfully prepared some sensors based on electrochemically reduced graphene oxide (ERGO) and its composites, with good results, such as detection of bisphenol A [39], vanillin [40], dopamine (DA) [41], rutin [42], etc. Based on the above research, we will propose a sensitive electrochemical detection method based on MnS/Co 3 S-ERGO nanocomposites, to provide better methods for AC detection. ...
... p is the peak current (A) and n is the number of electrons participating in the reaction. The symbols D, C, and v represent the diffusion coefficient of K 3 [Fe(CN) 6 ] (7.6 × 10 -6 cm 2 s − 1 )[42], the concentration of K 3 [Fe(CN) 6 ] (mol cm − 3 ) and the scan rate (V s − 1 ), respectively. After calculation, the effective active areas of bare GCE, GO/GCE, MnS/Co 3 S 4 /GCE, ERGO/GCE and MnS/Co 3 S 4 -ERGO/GCE were 0.064 cm 2 , 0.014 cm 2 , 0.078 cm 2 , 0.097 cm 2 and 0.11 cm 2 , respectively. ...
In this work, hollow tubular manganese-cobalt sulfide (MnS/Co3S4) hybrids were synthesized using a hydrothermal method and anchored on graphene oxide (GO) by simple ultrasonic dispersion. The nanocomposites were modified onto glassy carbon electrode (GCE) surface by a drop-coating method. After potentiostatic reduction, GO was converted into electrochemically reduced graphene oxide (ERGO), and a sensitive sensor, denoted as MnS/Co3S4-electrochemically reduced graphene oxide modified glassy carbon electrode (MnS/Co3S4-ERGO/GCE), was constructed for acetaminophen (AC) detection. The electrochemical sensing performance of MnS/Co3S4-ERGO/GCE was evaluated in detail. The experimental results show that MnS/Co3S4-ERGO/GCE has excellent electrocatalytic activity for the oxidation of AC. The kinetic process for the electrooxidation of AC on the MnS/Co3S4-ERGO/GCE was studied and the measurement parameters optimized. Under optimal conditions, the oxidation peak current is linear with the concentration of AC in the range of 0.01–20 μM and 20–80 μM, with a detection limit of 6.0 nM. Based on the high sensitivity and excellent selectivity of MnS/Co3S4-ERGO/GCE, the method has been applied for the determination of AC in commercial tablets and human serum samples, with satisfactory recoveries of 98.8%–101.5% and 98.6%–102.8%, indicating high accuracy of the proposed method.
... Integrating magnetite NPs with proper supporting materials is an effective strategy to maintain their distinguished characteristics. In this regard, GR is one of the carbonaceous nanostructures whose efficiency has been demonstrated as a catalytic support [28,29]. Several methods can be applied for the synthesis of Fe 3 O 4 NPs, but to avoid the problems of NPs production through usual physical and chemical methods (e.g., employing toxic reagents, multistep processes, and requiring high energy), biological synthesis can be replaced [30]. ...
... 40 Among the carbon nanomaterials, graphene, a two-dimensional carbon material, has been widely used in electrochemical nitrite designs due to its unique electrochemical properties, including high surface to volume ratio, high electrical conductivity, wide electrochemical voltage range, and fast heterogeneous electron transfer. 41,42 Several comprehensive reviews involving various nanofabricated graphene composite based nitrite sensors have been published, demonstrating the great potential of graphene in this analytical research area. 31,40,43 Moreover, graphene-based electrochemical sensors have been applied to measure nitrite in biological samples, including work in human urine samples. ...
In this work, we studied several important parameters regarding the standardization of a portable sensor of nitrite, a key biomarker of inflammation in the respiratory tract in untreated EBC samples. The storage of the EBC samples and electrical properties of both EBC samples and the sensor as main standardization parameters were investigated. The sensor performance was performed using differential pulse voltammetry (DPV) in a standard nitrite solution and untreated EBC samples. The storage effect was monitored by comparing sensor data of fresh and stored samples for one month at -80 °C. Results show, on average, a 20 percent reduction of peak current for stored solutions. The sensor's performance was compared with a previous EBC nitrite sensor and chemiluminescence method. The results demonstrate a good correlation between the present sensor and chemiluminescence for low nitrite concentrations in untreated EBC samples. The electrical behavior of the sensor and electrical variation between EBC samples were characterized using methods such as noise analysis, electrochemical impedance spectroscopy (EIS), electrical impedance (EI), and voltage shift. Data show that reduced graphene oxide (rGO) has lower electrical noise and a higher electron transfer rate regarding nitrite detection. Also, a voltage shift can be applied to calibrate the data based on the electrical variation between different EBC samples. This result makes it easy to calibrate the electrical difference between EBC samples and have a more reproducible portable chip design without using bulky EI instruments. This work helps detect nitrite in untreated and pure EBC samples and evaluates critical analytical EBC properties essential for developing portable and on-site point-of-care sensors.
... In addition, graphene and some of its derivatives, including graphene oxide (GO) and reduced graphene oxide (rGO), have been applied to detect substances in different food samples. These include colorants in food and drinks (He et al., 2018a;Qiu et al., 2016), heavy metal ions (Xia et al., 2015), antibiotic residues , dopamine, rutin from human samples He et al., 2018b;He et al., 2019a), pesticide residues , and 4nitrophenol (He et al., 2019b) from environmental contaminants. GO and rGO showed great promise in developing chemically modified electrodes (Shao et al., 2010). ...
Graphene and its derivatives have been a burning issue in the last 10 years. Although many reviews described its application in electrochemical detection, few were focused on food detection. Herein, we reviewed the recent progress in applying graphene and composite materials in food detection during the past 10 years. We pay attention to food coloring materials, pesticides, antibiotics, heavy metal ion residues, and other common hazards. The advantages of graphene composites in electrochemical detection are described in detail. The differences between electrochemical detection involving graphene and traditional inherent food detection are analyzed and compared in depth. The results proved that electrochemical food detection based on graphene composites is more beneficial. The current defects and deficiencies in graphene composite modified electrode development are discussed, and the application prospects and direction of graphene in future food detection are forecasted.
... Corrosion parameters including corrosion potential (Ecorr) and corrosion current (Icorr) can be calculated from the potentiodynamic polarization curve by Tafel extrapolation. The polarization resistance (Rp) can be calculated by the following formula [44,45]: ...
... 35 Moreover, it has been widely used in many sensors to detect some substances in vivo and in vitro, such as dopamine (DA), ascorbic acid (AA) and uric acid (UA), 35 as well as the content of antibiotics, such as sulfadiazine. 33 Fe 3 O 4 is a popular material with different magnetic properties from general materials, which has been put into widespread application, 36,37 such as sensors, 38 immunomagnetic microspheres, self-assembled enzyme 39 and sewage decontamination, 40,41 etc. ...
A functionalized nanocomposite composed of multi-wall carbon nanotubes (MWCNTs), Fe3O4 nanoparticles (Fe3O4), and β-cyclodextrin (CD) was prepared. The MWCNTs-CD-Fe3O4 modified glassy carbon electrode (GCE) displayed good electrochemical response toward rutin (Ru). The detection linear range and the detection limit of the electrochemical sensor for Ru were 0.02-10 µM and 16.4 nM, respectively. The results of actual sample detection were consistent with those of ultra-high performance liquid chromatography (UHPLC). The modified materials were also analyzed by UV-visible spectroscopy，transmission electrode microscope, and electrochemical impedance spectroscopy, respectively. The prepared nanocomposites integrate the excellent electric conductivity and electrocatalytic activity of MWCNTs and Fe3O4, as well as the disperse ability of CD, and may play a synergistic role in the electrochemical response of the modified electrode towards Ru. Moreover, the prepared sensor had good anti-interference ability and potential application in the actual content detection of drugs.
