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Background: Subcutaneous soft tissue metastasis of follicular thyroid carcinoma (FTC) is rarely diagnosed before surgery for clinicians. Case Report: We present a case of a 67-year-old man with a history of FTC and papillary thyroid microcarcinoma for 5 years. Multiple protruding subcutaneous nodules of the neck were found and removed from the surf...
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... histopathologic examination of these nodules was FTC, invading the surrounding striated muscle, adipose tissue and vessels. Under the microscope, the tumor cells were arranged in the form of small follicles, with acidophilic cytoplasm, enlarged, hyperchromatic nuclei and vascular invasion (Figure 3). Immunohistochemistry revealed the tumor cells to be positive for Tg and TTF-1. ...
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Background: Most patients with thyroid cancer typically receive thyroidectomy with ablative radioactive iodine therapy. Such patients were followed with thyroid ultrasonography and serial serum thyroglobulin evaluation. Exosomes are nanovesicles secreted into extracellular environments, including plasma, saliva, urine, and other body fluids of pati...
Citations
... In our case, the metastatic site was the soft tissue between the skin and the suprascapular region with destruction of the acromion process and lateral end of the clavicle, along with a well-defined radio opaque nodule in the right upper zone at the level of the right 6th rib. Similar findings were seen by Wang et al. and Fan et al [5,6]. Kelessis et al. described a case of painless supraorbital swelling in a 72-year-old woman with underlying bone destruction that proved to be metastasis from a well-differentiated thyroid carcinoma [7]. ...
... However, there are no fixed criteria for the diagnosis of follicular carcinoma on ultrasonography alone. Wang et al. also mentioned similar findings in their study [5]. ...
A-60-year-old elderly female presented with long standing swelling over the right shoulder. Thyroid was enlarged on examination and along with the routine work-up of patient, serum thyroid function test; Ultrasonography and Chest X-ray were performed. FNAC was performed from both the swellings i.e., thyroid gland and shoulder, and a provisional diagnosis of metastatic follicular carcinoma of thyroid was made A combination of proper history, along with serological markers, and fine needle aspiration cytology findings are necessary to make a provisional diagnosis of thyroid neoplasms. Also, a long term follow up is necessary to knock down the impact of metastases in previously diagnosed follicular thyroid carcinomas.
