FIGURE 3 - uploaded by Antonio Pesce
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Flebography of distal portion of the superior mesenteric vein showing the neoplastic occlusion of the vein.
Source publication
Portal-mesenteric tumor thrombosis represents a rare finding in patients with colorectal cancers. To our knowledge this is the first report of a patient diagnosed as having a wide stenosing right colon cancer with portal-superior mesenteric vein tumor thrombosis at the time of diagnosis, who was treated before surgery by positioning a percutaneous...
Context in source publication
Context 1
... by using a 4 French bern shaped tip catheter and a 0.035 inch hydro- philic wire (Terumo, Tokyo, Japan). The thrombus was partially aspirated by using a manual aspiration with a 50 mL luer lock syringe and a 7 French guiding catheter (Mach II, Boston Scientific); then 2 metal stents (Optimed, Germany) were deployed up to the main portal vein (Fig. 3). The aspirated material was sent for cytologic examination that confirmed the neoplastic origin of portal thrombosis. The thrombus and stent in the main portal vein were negotiated to the splenic vein and a second stent was deployed from the latter vein to the main portal vein (Fig. 4). After dilatation, the free flow stents were ...
Citations
... Previous experimental studies have proven that transhe-patic puncture and catheterization in a porcine model can be technically feasible without bleeding complications. 29 In our study, ultrasound was used to assess intrahepatic vascular dissection and provided clear guidance for PV puncture. Moreover, owning to fine needle puncture, no bleeding or hematoma was observed after operation. ...
Background and aims:
Endovascular implantation of iodine-125 (125I) seeds strand combined with stent is an effective method of treatment for portal vein tumor thrombosis. The aim of this study was to develop a novel endovascular brachytherapy stent (EVB-Stent) and to evaluate its feasibility of use.
Methods:
An EVB-Stent was implanted into the main portal vein (MPV) in a live porcine model via the percutaneous transhepatic route. Blood samples were collected and tested before and after operation, as well as before euthanasia. Single-photon emission computed tomography (SPECT) combined with CT (SPECT/CT) scan were performed directly after operation and CT scan was performed 2 months after implantation. After the CT scan was performed, all animals were euthanized and histologically examined.
Results:
The novel stent was successfully positioned in all six pigs. No deterioration of liver function was observed during the 2-month follow-up period. SPECT/CT revealed the uniform distribution of radiation around the seeds strand, and the hottest spot was near the center of the MPV. The patency of the stented MPV was confirmed using CT scans. The tissue-accumulated absorbed dose was 31,822.11 mGy at 10 mm transversely away from the midpoint of the 125I seeds strand, with a half-life of 59.4 days. Pathological examination results showed no significant atrophy or inflammation of adjunct liver tissue, and no obvious intima thickening or thrombosis were detected in the stented MPV.
Conclusions:
A liver porcine model was used to demonstrate that the transhepatic placement of a novel endovascular brachytherapy stent, EVB-Stent, is both technically feasible and safe.
