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Melasma is an acquired hypermelanosis that occurs exclusively in sun-exposed area mostly on face and rarely on the neck and forearms. It is more common in women and in Asians. Exact pathogenesis remains elusive, however, genetic predisposition and ultraviolet light exposure seem to play an important role.
The aim of this study was to evaluate facia...
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... of 110 patients 99(90%) had Fitzpatrick skin type IV, followed by Fitzpatrick skin type V in 6(5.5%) patients and Fitzpatrick skin type III in 5(4.5%) patients (Table 3). ...Context 2
... of 110 patients 99(90%) had Fitzpatrick skin type IV, followed by Fitzpatrick skin type V in 6(5.5%) patients and Fitzpatrick skin type III in 5(4.5%) patients (Table 3). ...Similar publications
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... Centrofacial pattern comprises 50-80% of cases, and it is present over the upper lip, nose and forehead, exclu-ding the chin and cheeks. 4 The malar pattern is present over the cheeks; on the other hand, the mandibular pattern is present over the chin and jawline. There are four types of melasma based on the depth of pigment deposition as determined by wood lamp examination. ...
... Centrofacial pattern comprises 50-80% of cases, and it is present over the upper lip, nose and forehead, exclu-ding the chin and cheeks. 4 The malar pattern is present over the cheeks; on the other hand, the mandibular pattern is present over the chin and jawline. There are four types of melasma based on the depth of pigment deposition as determined by wood lamp examination. ...
Objective: To evaluate the estrogen, progesterone, Prolactin and testosterone serum levels in melasma patients. Study Design: Comparative cross-sectional study. Place and Duration of Study: Dermatology Department, Fauji Foundation Hospital, Rawalpindi Pakistan, from Jul to Dec2020. Methodology: A total of 40 patients with melasma and 40 without melasma were included in this study. The study comprisedfemale melasma patients aged 20 to 50 years old. All participants were tested for serum estrogen, progesterone, Prolactin andtestosterone levels using immunoassay in the follicular phase (9th day) of the menstrual cycle. Results: The statistically significant increase in serum progesterone (p=0.001) was found in patients with melasma. Asignificant decrease in prolactin levels (p=0.0001) was found in patients with melasma. No association was found betweenGroup-1 and Group-2 regarding serum estradiol and testosterone (p=0.070 and p=0.461 respectively) Conclusion: Patients with melasma have increased progesterone levels and decreased serum prolactin levels.
... In another study conducted by Neema et al [17] it was found out that reticuloglobular pattern was seen in 83(83%) of patients followed by perifollicular brown black globules in 60(60%) of the patients. Granules/dots formed 28(28%) of patients and unpatterned pigmentation in 17(17%) of the patients. ...
... Granules/dots formed 28(28%) of patients and unpatterned pigmentation in 17(17%) of the patients. In a similar study conducted by Neema et al [17] telangiectasia was observed in 33(33%) of patients. This is in accordance with our study as our study showed similar results. ...
Objectives: This study was to evaluate the clinical profile and dermatoscopic classifications of melasma. Methods: A detail assessment, clinical examinations were performed to all patients. Clinical photographs were taken with full precautions to minimize the expression of the identity of the patient. Dermatoscopic evaluation of each subject was done. A USB Digital Magna-scope with 8LED light source, 20x to 200x magnification and 2Mega Pixel image sensor was used for dermatoscopic evaluation. Results: Most common dermatoscopic pattern was sparing of follicles 78(78%) followed by brown pigment 54(54%), accentuation of psuedonetwork 42(42%), brown –grey pigment 8(8%), grey pigment 11(11%) and perifollicular accentuation 4(4%). Telengiectasia was seen in 25(25%) patients. Conclusions: Melasma is more preponderance in middle age female. Most common factors for melasma are sun exposure and usage of fairness cream. Centrofacial is the most common type of melasma followed by malar. Sparing of follicles is one of the most common patterns of melasma on dermatoscopy. Hence, Melasma is a common acquired facial hyperpigmentary disorder which can cause a significant psychosocial impact in the patient. Dermatoscopy is a simple, non-invasive, office tool which helps in an accurate classification, early identification and therapeutic monitoring of melasma.
