Figure 1 - uploaded by Issam Al Jajeh
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First conjunctival nodule at the right nasal limbus A) Right nasal limbus showing a vascularised conjunctival nodule before biopsy B) Right nasal limbus 9 months after excision biopsy, cryotherapy, conjunctival grafting with fibrin glue C) Conjunctival biopsy showing actinic keratosis with squamous epithelial hyperplasia, hyperkeratosis and mild basal atypia. (Hematoxylin/ Eosin X100).
Source publication
Xeroderma pigmentosum (XP) is a rare genetic disease associated with hypersensitivity to ultraviolet radiation resulting in cutaneous, ocular and neurological abnormalities. Ocular involvement typically includes photophobia, keratitis, corneal opacity and atrophy of the eyelids, along with carcinomas and melanomas. We report a rare case of conjunct...
Contexts in source publication
Context 1
... parents and elder sister were unaffected. He had no significant ocular involvement except mild photophobia and conjunctival injection until October 2011 when he presented with a right nasal conjunctival nodule with pigmentation noted inferior to the nodule ( Figure 1A and 1B). Excision biopsy, cryotherapy and conjunctival graft with fibrin glue were performed. ...
Context 2
... examination showed actinic keratosis ( Figure 1C) and atypical secondary acquired melanosis (Figure 2A-2C). Post- operative recovery was uneventful. ...
Context 3
... is likely that the delay in removal resulted in the lesion progressing to CIN2. Histopathologically, the first conjunctival biopsy showed hyperplastic squamous epithelium with hyperkeratosis and basal cell atypia in basal zone ( Figure 1C) as well as atypical secondary acquired melanosis. The latter manifested as proliferation of mildly atypical pigmented cells predominantly in basal zone (Figure 2A). ...
