Fig 1 - uploaded by Toru Obata
Content may be subject to copyright.
Findings on computed tomography scan and during surgical procedure. [A] Abdominal computed tomography demonstrates free air and feces out of intestinal rumen in the peritoneal cavity. [B] Massive feces were observed in the abdominal cavity. 

Findings on computed tomography scan and during surgical procedure. [A] Abdominal computed tomography demonstrates free air and feces out of intestinal rumen in the peritoneal cavity. [B] Massive feces were observed in the abdominal cavity. 

Source publication
Article
Full-text available
We report two cases of septic shock in which plasma endotoxins were detected by a novel endotoxin detection method, named endotoxin scattering photometry (ESP) method. Case1: An 85-year-old female was diagnosed with peritonitis caused by sigmoid colon perforation. The patient presented with septic shock after Hartmann’s procedure. Reduction in the...

Contexts in source publication

Context 1
... LAL assay. We also demonstrated that the reductions in plasma endotoxin levels were accompanied with the improvement of hemodynamic conditions. The laboratory data were as follows: white blood cell count, 3,700/mm 3 ; C-reactive protein (CRP) lev- el, 0.06 mg/dL. The patient was diagnosed as hav- ing perforation of sigmoid colon by abdominal CT (Fig. 1A ). An emergent laparotomy was performed through a median abdominal incision. There was a large amount of feces and foul-smelling dirty ascites in the abdominal cavity (Fig. 1B ). An approxi- mately 10-mm perforation of sigmoid colon was not- ed. The perforated sigmoid colon was partially re- sected. The proximal descending colon was ...
Context 2
... white blood cell count, 3,700/mm 3 ; C-reactive protein (CRP) lev- el, 0.06 mg/dL. The patient was diagnosed as hav- ing perforation of sigmoid colon by abdominal CT (Fig. 1A ). An emergent laparotomy was performed through a median abdominal incision. There was a large amount of feces and foul-smelling dirty ascites in the abdominal cavity (Fig. 1B ). An approxi- mately 10-mm perforation of sigmoid colon was not- ed. The perforated sigmoid colon was partially re- sected. The proximal descending colon was diverted and a single-barrel colostomy was per- formed. Enterobactor cloacae, Enterococcus sp. Bacteroides fragilis were cultured from the ascites. The endotoxin level measured ...

Similar publications

Article
Full-text available
Background: Severe sepsis and septic shock are common in intensive care and carry high mortality rates. In patients with Gram-negative infections, early and extensive removal of endotoxin may limit the inflammatory response that characterizes septic shock. The Alteco® LPS Adsorber (hereafter referred to cited as the lipopolysaccharide (LPS) Adsorb...
Article
Full-text available
Sepsis is a deadly disease that is widely attributed to endotoxin released by gram‐negative bacterial infections often plague emergency care facilities. Conventionally antibiotics and vasopressors are used to treat this disease. Recent treatment protocol shifted to a membrane to remove the offending endotoxin monomer. Despite this shift, membrane‐b...
Article
Full-text available
Sepsis and septic shock are associated with high mortality and neurodevelopmental impairment in preterm infants. Recently, endotoxin and mediator removal using a polymyxin B-immobilized fiber column for direct hemoperfusion (PMX-DHP) has been used for the management of septic shock even in neonates. Although early withdrawal from shock with PMX-DHP...
Article
Full-text available
Plasmapheresis is an extracorporeal technique that eliminates macromolecules involved in pathological processes from plasma. A review is made of the technical aspects, main indications in critical care and potential complications of plasmapheresis, as well as of other extracorporeal filtration techniques such as endotoxin-removal columns and other...
Article
Full-text available
Endotoxin, a component of the cell membrane of gram-negative bacteria, is a trigger for dysregulated inflammatory response in sepsis. Extracorporeal purification of endotoxin, through adsorption with polymyxin B, has been studied as a therapeutic option for sepsis. Previous studies suggest that it could be effective in patients with high endotoxin...