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![A) Peripheral blood smear (Leishman stain, magnification ×100) shows increased platelets and platelet clumps. (B) Bone marrow aspirate (Giemsa stain, magnification ×40) shows cellular marrow with megakaryocytes cluster (inset: hyperlobated megakaryocyte). (C) Bone marrow biopsy shows increased number of megakaryocytes with hyperlobated nuclei (hematoxylin and eosin stain [H&E], magnification ×40). (D) Photograph of resected spleen with pale cut surface. (E) Photomicrograph of spleen shows infarcted areas (H&E, magnification ×40).](publication/361315833/figure/fig1/AS:11431281100066154@1669320278050/Figure-A-Peripheral-blood-smear-Leishman-stain-magnification-100-shows-increased.jpg)
A) Peripheral blood smear (Leishman stain, magnification ×100) shows increased platelets and platelet clumps. (B) Bone marrow aspirate (Giemsa stain, magnification ×40) shows cellular marrow with megakaryocytes cluster (inset: hyperlobated megakaryocyte). (C) Bone marrow biopsy shows increased number of megakaryocytes with hyperlobated nuclei (hematoxylin and eosin stain [H&E], magnification ×40). (D) Photograph of resected spleen with pale cut surface. (E) Photomicrograph of spleen shows infarcted areas (H&E, magnification ×40).
Source publication
Background: Essential thrombocythemia is a chronic myeloproliferative neoplasm characterized by thrombotic and hemorrhagic complications. Essential thrombocythemia can be considered a risk factor for thrombotic events.
Case Report: A 34-year-old female presented with sudden onset of abdominal pain from splenic infarction for which she underwent spl...
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Background
Essential Thrombocythemia is a chronic myeloproliferative neoplasm characterized by an isolated excessive production of platelets. Extreme thrombocytosis is defined by having a platelet count greater than or equal to 1,000 x 10⁹/L, which may lead to the development of acquired von Willebrand syndrome and complications of excessive hemorr...
