Fig 4 - uploaded by Aisha Jamal
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Context 1
... Bone marrow aspirate and trephine biopsy was performed. Aspirate washemodiluted ( Fig. 3) with occasional blast cells. Trephine biopsy was cellular (80% cellularity) with marked megakaryocytic hyperplasia and features of dysmegakayopoesis, like monolobation and hypolobation. Micromegakaryocytes were also identified on trephine biopsy sections (Fig. 4).Trephine biopsy also revealed markedly increased fibrotic activity that was causing streaming of cells and distortion of morphology. Reticulin stain showed MF-2 fibrosis (Fig. 5). Immunohistochemistry was performed that showed CD34 positivity in around 3% of cells while CD61 was positive in megakaryocytes and micromegakaryocytes (Fig. ...
Context 2
... Bone marrow aspirate and trephine biopsy was performed. Aspirate washemodiluted ( Fig. 3) with occasional blast cells. Trephine biopsy was cellular (80% cellularity) with marked megakaryocytic hyperplasia and features of dysmegakayopoesis, like monolobation and hypolobation. Micromegakaryocytes were also identified on trephine biopsy sections (Fig. 4).Trephine biopsy also revealed markedly increased fibrotic activity that was causing streaming of cells and distortion of morphology. Reticulin stain showed MF-2 fibrosis (Fig. 5). Immunohistochemistry was performed that showed CD34 positivity in around 3% of cells while CD61 was positive in megakaryocytes and micromegakaryocytes (Fig. ...
