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Inhibition of α-glucosidase activity by red dragon fruit pulp and peel extracts. (A higher resolution / colour version of this figure is available in the electronic copy of the article).

Inhibition of α-glucosidase activity by red dragon fruit pulp and peel extracts. (A higher resolution / colour version of this figure is available in the electronic copy of the article).

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Background: Diabetes mellitus is a chronic metabolic condition marked by persistently elevated blood sugar levels. Key digestive enzymes viz. α-amylase and α-glucosidase, hydrolyze consumed carbohydrates into glucose which raises the postprandial blood glucose level in a diabetic patient. So, the development of α-amylase and α-glucosidase inhibitor...

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Context 1
... antidiabetic drug acarbose (66.45 ± 1.78%), which has an IC 50 value of 679.19 µg/mL at the same concentration. However, red dragon fruit peel extracts displayed α-glucosidase inhibition activity (46.63 ± 3.83%) comparatively lower than red dragon fruit pulp extract at the same concentration with a calculated IC 50 value of 1064.58 µg/mL (Fig. 4, Table ...