Fig 26 - uploaded by Michael S Hofman
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7 SPECT/CT and characterisation of benign bony disease. Three women with mid thoracic back pain with past history of breast carcinoma. Posterior planar ( left ), SPECT/CT ( centre ) and CT ( right ) shown. Top : planar image ( a ) demonstrates linear uptake in T8 vertebral body. SPECT/CT ( b , c ) demonstrates a T8 wedge compression fracture with marked scalloping of the superior end plate but without features to suggest malignant aetiology. Follow-up with CT at 12 months (not shown) demonstrated no interval change and con fi rmed benign aetiology.
Source publication
cancer of the breast, the bones suffer in a special way, which cannot be explained by any theory of embolism alone (Paget 1989) . This was the fi rst description of the preferential metastasis and growth of breast cancer cells in bone. Breast cancer is a heteroge-neous disease composed of several biologic sub-types with distinct behaviour and varia...
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Citations
Uptake in nonosseous, nonurologic tissues is occasionally found in the performance of bone scintigraphy. Proper interpretation of these cases depends on identifying the involved organs and appreciating the significance of the uptake. Because of the rarity of these findings and a relative de-emphasis of planar imaging in radiologic imaging, current era trainees may exhibit difficulty in identifying organs on planar projections. The first section of this work consists of an image atlas depicting uptake by various nonosseous, nonurologic organs on planar scintigraphy. In the second section, we discuss the etiologies of soft-tissue uptake, organized according to mechanisms of accretion: (1) metastatic calcification, (2) dystrophic calcification, (3) metabolic uptake, and (4) compartmental sequestration. Spurious or artifactual uptake represents a fifth category of apparent soft-tissue uptake which will also be reviewed. Causes of organ uptake span the gamut of trivial and artifactual to those reflecting serious malignant and systemic disorders. Clues as to etiology may be gleaned from grouping of abnormalities.
