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Fibrin clot in plasma ampulla. (A) A large aggregate of fibrin clots was formed in the plasma ampulla when the second filter was not anticoagulated. (B) No apparent fibrin clot formation was observed in the plasma ampulla following the anticoagulation of the second filter.
Source publication
Regional citrate anticoagulation (RCA) has been widely used in patients with high-risk bleeding for anticoagulation in renal replacement therapy. However, scientific reports on the use of RCA in double-filtration plasmapheresis (DFPP) are limited. In the available reports, anticoagulation was not performed in the plasma component separator. However...
Contexts in source publication
Context 1
... pulp waste was 400-500 ml. Sodium citrate (4%) was used as the anticoagulant with a speed of 150 ml/h in the first filter and 50 ml/h in the vein ampulla for DFPP. The second filter was clogged at ~1.5 h following the commencement of DFPP, and it was found that a large number of fibrin clots were formed in the second filter and plasma ampulla ( Fig. 2A). As the coagulation of the second filter hindered the treatment process, citrate was administered to the first filter, the second filter and vein ampulla at the same time. Sodium citrate (4%) was administered at a speed of 150 ml/h in the first filter, 50 ml/h in the second filter and 50 ml/h in the vein ampulla (Fig. 3). After ...
Context 2
... was administered to the first filter, the second filter and vein ampulla at the same time. Sodium citrate (4%) was administered at a speed of 150 ml/h in the first filter, 50 ml/h in the second filter and 50 ml/h in the vein ampulla (Fig. 3). After adjusting the anticoagulant regimen, no coagulation occurred in the second filter or plasma ampulla (Fig. ...
