Figure 2 - available via license: Creative Commons Attribution 4.0 International
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Example of output Excel file.
Source publication
Genome-scale metabolic models of microbial metabolism have extensively been used to guide the design of microbial cell factories, still, many of the available strain design algorithms often fail to produce a reduced list of targets for improved performance that can be implemented and validated in a step-wise manner. We present Comparative Flux Samp...
Contexts in source publication
Context 1
... analysis methods based on Kolmogorov-Smirnov test have been implemented using scipy stats package. Besides distribution plots, the output of CFSA includes a summary Excel file (Figure 2). The summary includes predicted gene targets sorted by the mean fold change between growth and production scenarios, their corresponding reactions, their essentially, correlation group, and the presence or absence of isoenzymes which might complicate in vivo implementation of down-regulations . ...
Context 2
... such as naringenin are precursors of anthocyanins and have traditionally been used for fragrance, flavour, and colour in various food types [35,36]. Naringenin is derived from the shikimate (SHK) pathway for aromatic amino acid biosynthesis, which starts with the condensation of erythrose-4-phosphate (E4P) and phosphoenolpyruvate (PEP) as illustrated in Figure 2 B. Production of this compound requires the heterologous expression of 4CL, CHS, CHI and either PAL, C4H and CPR or TAL (Table 1), as well as an appropriate supply of malonyl-CoA [37]. ...
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