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Évolution de la croissance mycélienne de Botrytis cinerea en fonction de différentes concentrations de deux sesquiterpènes d'Asteriscus graveolens subsp. odorus durant les 7 jours d'incubation.
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Two sesquiterpenes of Asteriscus graveolens subsp. odorus, have been extracted, separated, purified and identified by NMR and IR: the naupliolide and asteriscunolide 3c. The valuation of these compounds is part of the search for a preventive approach of integrated control to reduce significantly the use of pesticides and especially the fungicide on...
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... effet, si le naupliolide présente de meilleurs résultats en termes d'inhibition de la croissance du Botrytis cinerea à des doses de 50, 100 et 125 ppm estimées par 50, 60,34 et 63,79%, l'asteriscunolide 3c, quant à lui, se présente plus efficace à des doses de 150 à 1000 ppm estimées de 81,3 à 100%. Toutefois, à 2000 ppm une inhibition complète similaire des deux produits a été notée (Figure 3 Test in vitro des sesquiterpènes d'Asteriscus graveolens subsp. odorus sur la croissance mycélienne du Penicillium digitatum Penicillium digitatum semble répondre sensiblement aux deux produits testés (Figure 4). ...
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10-oxodehydrobotrydial (1) and 4β-Acetoxy-9β,10β,15α-trihydroxyprobotrydial (2) have been isolated from Hypoxylon rickii mycelia extract. Compound 2 is probably an intermediate of botrydial, which is a known sesquiterpene phytotoxin. Cluster Omega and Artemis software analysis suggested that HRT6, a possible botrydial-like gene cluster with four ge...
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... In folk medicine, AG is used for various diseases such as fever, gastrointestinal tract complaints, headache and bronchitis. Several studies have shown that the plant has an anti-inflammatory 3 , an antibacterial [5][6] and an antifungal effect [2][3][4][5][6][7] . Furthermore, AG EO exhibits different biological activity such as antioxidant, antibacterial, antifungal, hemolytic, anticancerous activity and anticorrosion activities 2-5-12 . ...
The objective of this work is the study of the chemical compositions, the acute toxicity and the anti-inflammatory activity of the essential oils (EOs) of the leaves and flowers from Asteriscus graveolens, collected in the southwest of Algeria. The chemical composition of EOs was established by gas chromatography (GC) and gas chromatography / mass spectrometry (GC/MS). The acute toxicity was assessed using Lorke's approach in Animal Models. The anti-inflammatory test was performed using an animal model and determined by carrageenan induced paw oedema. Thirty-four compounds were identified, accounting for 98.7 and 99.25% of the total EOs of leaves and flowers respectively. The major chemical components characterizing the EOs were oxocyclonerolidol, cis-chrysanthenyl acetate and cis-acetoxychrysanthenyl acetate, but the percentage of each compound varied depending on the EOs. The results obtained from the anti-inflammatory test showed that the EOs have a very high anti-inflammatory power with a dose dependent effect.
... Following our literature search, the literature on the study of the biological activity of this plant is limited to 9 articles, 3 of which deal with its antibacterial activity [8][9][10] . Other articles by Alilou et al. and Znini et al. showed a considerable antifungal effect 11,12 . Another study was carried out by Znini et al. on the effect of EO from A. graveolens leaves on corrosion inhibition 13 . ...
The objective of this study is the evaluation of the central and peripheral analgesic activity of the leaves and flowers Essential Oils (EOs) of Asteriscus graveolens as well as their acute toxicity. The pharmacological tests were performed using an animal model. Acute toxicity was determined by Lorke's method. Central analgesic activity was evaluated by the hot plate test, and peripheral analgesic activity was conducted by the writhing test. The results showed that the EOs of A. graveolens from both organs are weakly toxic. For the central analgesic activity, the results revealed that leaf EO have a remarkable antinociceptive effect compared to flowers EO with a maximum latency time of the animals on the hot plate on the order of 22.5 seconds. Finally, the peripheral analgesic activity revealed a maximum inhibition of abdominal writhing of 99% for flowers EO and 96% for leaves EO. Keywords: Asteriscus graveolens, analgesic activity, toxicity.
... In case of Penicillium expansum, the concentrations 46-93 μg/ml exhibit similar behaviours, this is the case of concentrations 140-180 μg/ml. This same result was found by Alilou et al., (2016) When talking about antifungal activity, there are two kinds of effects: lethal or fungicidal activity and inhibition of growth or fungistatic activity [12]. According to Beigi Boroujeni & Gholami (2017); Ulanowska et al., (2006), the sage has an effect fungistatic, this activity is mainly due to the ability of flavonoids to inhibit the expression of DNA and the synthesis of certain enzymes and membrane proteins of microorganisms. ...
Medicinal plants constitute an immense source of bioactive molecules, endowed with numerous biological activities. This study aimed at performing antioxidant and antifungal screening of flavonoids extract from Salvia officinalis leaves, this plant with therapeutic properties serving to the curative needs of certain peoples An antioxidant and antifungal test were performed after the extraction of flavonoids, which are in the value of 6.96%. Antioxidant activity of Salvia officinalis flavonoids was evaluation by the DPPH test revealed a fairly high anti-radical effect with results ranging from 75.67% to 90.27% and an effective concentration to reduce 50% of free radicals of 10.60 μg / ml. The evaluation of antifungal activity was fined by radial growth technique gave the antifungal indices according to the order of efficacy of the flavonoids; on the following recorded antifungal registers; Aspergillusflavus 24.16%, A.ochraceus 21.61%, A. niger 20.16% and P.expansum 16.95%.
Background: Medicinal plants constitute an invaluable source of natural substances which can be used in the formulation of new antifungal agents. Among these medicinal plants, the genera Ephedra alata and Bubonium graveolens are used in traditional medicine. In the search for molecules bioactives, resource exploration natural, especially plants medicinal, appears as a track promising because they constitute, by their biodiversity, a great reserve of active substances. This study aimed to evaluation antifungal activity of medicinal plant extracts Bubonium graveolens and Ephedra alata against two fungi namely, Penicillium sp and Aspergillus niger. Method: During our work, we prepared the various extracts (aqueous, methanolic and ethyl acetate) for the plants studied, the search for the active compounds of these two species by the extraction method was essentially based. The antifungal tests were investigated by using agar medium methos The tests is estimated by determining the diameters of zone inhibition and growth inhibition rate PI %. Result: The results obtained show that the aqueous extracts of Ephedra alata and Bubonium graveolens are inactive against two fungi in our study. However, methanol and ethyl acetate extracts showed very good activity antifungal against the fungal species tested. The evaluation of the antifungal activity of the methanolic and ethyl acetate extracts had a higher activity (99,70 ±0,240) against all the molds tested compared to the aqueous extract (63,52 ±0,959). The extracts of Ephedra alata and Bubonium graveolens significantly inhibited the growth of the two fungi tested. These three extracts showed a good antifungal effect at the laboratory scale. Ours finding demonstrate that Bubonium graveolens and Ephedra alata extracts possesses antifungal activity that might be a natural potential source antifungal compounds used in pharmaceuticals products, cosmetics and food
