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Evidence of large anelastic area in correspondence of the solid lesion located at the level of the corpora cavernosa and the intercavenospongiousus septum with normal elasticity of peripheral tissues.
Source publication
Metastatic penile carcinoma derived from cholangiocarcinoma (CCA) has not been previously reported in the literature. Common metastatic sites for CCA include the regional lymph nodes and adjacent organs. CCAs are not highly vascularised tumours, making hematogenous metastases uncommon. Hematogenous CCA metastases commonly occur at distant organs su...
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Citations
... Реже встречаются метастазы из опухолей прямой кишки [16][17][18], почки [19] (во всех наблюдениях левой). В качестве казуистической редкости описаны метастатические опухоли полового члена при раке легких, носоглотки, печени, ободочной кишки, желчных путей [20]. Вторичная опухоль полового члена может появиться через длительное время после удаления первичного опухолевого очага даже через 5 лет. ...
Tumors of the penis (both malignant and benign) are fairly rare diseases. Even more rare are cases of metastasis of malignant tumors of other organs to penis. The clinical picture of penile metastatic lesions is highly heterogeneous, ranging from small nodules to massive lesions with or without ulceration, obstructive or irritative symptoms, hematuria or priapism. This article reviews the literature on this rare nosology, as well as from personal experience presents a clinical observation of a rare disease: priapism secondary to bladder cancer metastasis.
... 9 The most common metastatic sites of ICC include the lymph nodes, peritoneum, lungs, and pleura. 10 ICC metastasis to the male urogenital tract is rare; [11][12][13] only two cases of testicular metastasis of ICC have been reported. 3,4 Our patient was initially diagnosed with ICC, with no evidence of seminoma at that time. ...
Testicular metastasis of solid tumors is uncommon. Common primary sites of metastatic tumors to the testis are the lungs and prostate. Cryptorchidism is associated with a four-fold increase in the risk of a testicular germ cell tumor of which seminoma is the most common type. We report an extremely rare case of a collision tumor that comprised testicular metastasis of intrahepatic cholangiocarcinoma and a seminoma in an undescended testis. To the best of our knowledge, this is the first case of this type of tumor to be described. Awareness that metastatic intrahepatic cholangiocarcinoma may present as a testicular tumor may aid diagnosis and management of such patients.
... With respect to the genitourinary system, no published cases involve the urinary components of the genitourinary system; the current literature regarding metastatic cholangiocarcinoma include only the penis, uterus, and ovary. [9][10][11] Bladder metastasis along with infiltration of the left psoas muscle may have contributed to hydronephrosis and acute kidney injury. ...
Cholangiocarcinoma offers poor prognosis. Infrequent sites of metastasis are poorly described and often diagnostically delayed or missed. Bile duct brush cytologies provide poor diagnostic sensitivity/specificity. We present an unusual case of cholangiocarcinoma in a 34-year-old woman with rare distant metastasis to the psoas muscle and urinary bladder. It is the first case of metastatic cholangiocarcinoma presenting as linitis plastica, and our patient is the youngest to be described with metastatic cholangiocarcinoma to the psoas muscle leading to diagnosis. We conclude that seemingly idiopathic biliary strictures that fail to respond to testing should prompt alarm and referral for cholangioscopy, where available.
... Only a few cases of ICC metastasizing to the male urogenital tract have previously been reported in literature [2][3][4]. These include metastasis in the testis [4], epididymis [2] and penis [3]. ...
... Only a few cases of ICC metastasizing to the male urogenital tract have previously been reported in literature [2][3][4]. These include metastasis in the testis [4], epididymis [2] and penis [3]. To our knowledge, this is the first described case of ICC metastasizing primarily to the prostate. ...
... In our case, even with the known history of the patient, the biopsy specimen is too small and we have used CK20, CK7, CDX2 and PSA, for an accurate diagnosis. Rare histologic types have been reported as penile secondary tumors, such as lung squamous carcinomas or adenocarcinomas, osteosarcoma, malignant melanoma, neuroendocrine tumors, sarcomas, cholangiocarcinoma etc. [3,12,13]. ...
Background: Despite its rich vasculature, the penis is rarely involved by metastasis. Since the first description of
penile metastasis in 1870, fewer than 500 cases have been reported in the literature. The pelvic organs are the main
source of primary tumors that metastasize to the penis.
Case presentation: We report a case of a 46-year-old Arabic man who presented with erectile dysfunction and
painful induration of the penile root. Eight months ago, he had undergone abdomino-perineal resection for rectal
adenocarcinoma after neo-adjuvant chemotherapy. The histological evaluation of the resected specimen disclosed a
ypT3N0 tumor with a poor therapeutic response (around 5%). An adjuvant chemotherapy by XELOX (oxaliplatin plus
capecitabine) regimen has been prescribed for the patient. The magnetic resonance imaging (MRI) showed tumoral
infiltration of penile structures and a biopsy of the corpora cavernosa was performed. The histological examination
disclosed a penile metastasis from the patient’s previous rectal adenocarcinoma. The patient is still alive and continues
his adjuvant therapy.
Conclusion: Penile secondary tumors are very rare and usually occur in patients with advanced tumor stages. A diagnosis
of penile metastasis should be considered in patients with a history of malignancies who present with genitourinary
symptoms. These patients have a dismal prognosis as they often die in the year after the diagnosis.
... All described cases were associated with very poor prognosisdvariable survival rates from 1 to 24 monthsdand in all these cases, autopsy has identified multiple coexistent sites of metastasis in the patients [5e7]. Only 2 articles from the recent literature have described a penile metastatic localization from osteosarcoma and cholangiocarcinoma [8,9]. ...
Penile metastasis from prostate cancer represents a rare condition, associated with poor prognosis. In the literature, authors have reported less than 500 cases of secondary penile cancers, and among these cases of metastases, only 33% are from prostate cancer. Overall reported rate of survival is about 1-24 months. Here, we present an uncommon case of penile metastasis from prostatic adenocarcinoma, with particular focus on the role of computed tomography and magnetic resonance imaging in diagnosis and follow-up.
... The most common symptoms and signs in order of frequency are priapism, urinary retention, penile nodules, ulcer formation, perineal pain, edema, generalized swelling, broad infiltrative enlargement, dysuria, and hematuria. 2 Our patient presented with penile nodule and intramuscular mass in the thigh, which is extremely rare. The patient was offered systematic chemotherapy and local radiotherapy and got partial relief. ...
We present a case with penile and intramuscular metastases of esophageal squamous cell carcinoma. A 61-year-old male had undergone a total esophagectomy and later developed metastatic nodules of the penis and intramuscular metastasis of the thigh. We believe this is the first report of this rare case. We describe the clinical manifestation and offer therapeutic regimen; we also summarize the relevant literature.
Male genital dermatoses present a diverse array of symptoms including itch, pain, cracking, blistering, bruising, dysuria and dyspareunia, and can affect quality of life in terms of sexual, dermatological, psychological and urological morbidity. Dermatoses such as psoriasis, lichen planus and atopic eczema may manifest in specific morphology in the genital region, while other dermatoses such as lichen sclerosus, have a genital predilection, and subtle clinical signs that require assiduous assessment and a trained eye to detect. Treatment may present similar challenges due to the essential functions and associated stressors in the region. Precancerous pathologies also present challenges in terms of clinical recognition, and treatment, with diverse morphologies and region‐specific predisposing factors, and surgical challenges in terms of preserving sexual and urinary function.
A number of common skin diseases affect the genital and genito‐crural skin only incidentally, and may present in these areas with unusual features. These are dealt with briefly or by cross‐reference to their full description elsewhere. However, those conditions that are entirely or predominantly confined to these regions are discussed in detail.
