Erythematous plaques on face and upper body as well as edema of the lips and eyelids.

Erythematous plaques on face and upper body as well as edema of the lips and eyelids.

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The novel coronavirus disease (COVID-19) that emerged in Wuhan, China in December 2019 quickly escalated to a global pandemic. Several studies have described its typical clinical manifestations, including fever, cough, diarrhea, and fatigue. In this study we characterize the dermatologic aspects of COVID-19 so that dermatologists may be aware of th...

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... 34-year-old woman with no history of urticaria and or angioedema presented with pruritic erythematous plaques on her face and upper body as well as edema of the lips and eyelids (Figure 1). She reported that her edematous rash had started 2 days earlier, followed by dry cough without fever. ...

Citations

... (5,10,12,29) Oral manifestations have appeared in healthy COVID-19 patients with no relevant medical history, (1,5,12,13,18,(30)(31)(32)(33) and in patients with underlying conditions. (1,7,10,12,13,16,18,23,(27)(28)(29)(30)(33)(34)(35)(36)(37)(38)(39)(40)(41) The manifestations that are mentioned more frequently are taste disorders and ulcers, while the least mentioned are pustules, glossitis, and geographic tongue. The main manifestations found are described below (Table 1): (1,(9)(10)(11)14,17,18,26,27,30,33,41,42,46) The location of lesions is unspecific, but they appear mainly on the palate, tongue (mainly on the dorsum), and also lip (inners side and semi mucosa). ...
... Palate 3 case reports 4 narrative reviews 1 systematic review 2 critical reviews 10 letters to the editor 1 observational study 1 clinical case with narrative literature review 22 references (1,6,9,(11)(12)(13)15,17,18,20,23,(26)(27)(28)(29)(30)(31)35,38,39,41,43) Tongue 5 case reports 2 narrative reviews 1 systematic review 2 critical reviews 11 letters to the editor 2 observational studies 1 clinical case with narrative literature review 24 references (1,5,6,(9)(10)(11)(12)17,20,23,(26)(27)(28)(29)32,33,35,38,39,41,(44)(45)(46)49) Lip 6 case reports 4 narrative reviews 1 systematic review 2 critical reviews 7 letters to the editor 2 observational studies 1 clinical case with narrative literature review 23 references (1,5,6,9,11,13,15,17,18,20,23,(26)(27)(28)(29)(30)34,37,38,41,42,46,49) Oral mucosa 2 case reports 2 narrative reviews 1 systematic review 1 critical review 3 letters to the editor 1 observational study 10 references (1,9,11,15,27,28,29,37,46.49) Gum 1 case report 3 narrative reviews 1 systematic review 1 critical review 5 letters to the editor 1 clinical case with narrative literature review 12 references (5,6,9,11,13,15,18,(26)(27)(28)41,48) Oropharynx 2 case reports 2 narrative reviews 1 systematic review 2 letters to the editor 1 observational study 8 references (5,10,11,13,18,23,27,31) ...
... (6,9,12,15,17,23,27,29,34) Similarly, oral mucosa lesions could be triggered by factors such as stress. (5,8,18,22,25,26,32,37) We must emphasize the importance of the ACE2 receptor, which is distributed in the cell membrane of various organs and tissues, such as the respiratory tract, the nervous system, the digestive system, and the skeletal muscle. (1,9,13,23,24,27) In the oral cavity, they appear in the oral (1,7,8,12,(16)(17)(18)(19)(21)(22)(23)(24)(25)(26)(27) and gingival (7,14,21,23,24) mucosa epithelial cells. ...
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Objective: Identify the main oral manifestations associated with COVID19 and describe their location in the oral cavity. Methods: The literature search was conducted in PubMed, Medline, LILACS, LIVIVO, Web of Science, and SciELO. The following words were searched for: oral mucosa, oral mucosa lesion, oral manifestations, COVID-19, and SARS-CoV-2. Duplicate articles were eliminated, and the pieces were shortlisted. Finally, inclusion and exclusion criteria were applied. Results: This study included 47 articles. The main oral manifestations in patients with COVID-19 are taste disorders, xerostomia, ulcers, vesicles, and others located in different areas of the oral mucosa. Conclusions More studies are needed to determine the potential oral etiopathogenesis of SARS-CoV-2. Moreover, dentists play a significant role in the multidisciplinary and telemedicine team.