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Erythematous-papular lesions with crusts and excoriations in scabies affecting both calves. Ryc.1. Zmiany rumieniowo-grudkowe, strupy i przeczosy w przebiegu świerzbu na obu podudziach.
Source publication
Introduction:
Scabies is a parasitic skin disease caused by Sarcoptes scabiei. About 200 million casesworldwide each year in people of all ages are reported.
Aim of study:
Retrospective analysis of records of patients hospitalized at the Department with scabies.
Materials and methods:
Six-year retrospective analysis of medical records of patie...
Contexts in source publication
Context 1
... predominant symptom is intense pruritus, often intensifying at night, caused by a delayed allergic reaction to the presence of the parasite itself, its faeces and eggs (1). The clinical features of scabies are papules with erosions and excoriations located around the wrists, fingers, elbows, armpits, genitals, torso and buttocks, in newborns and children lesions can also occur on the head and face (1) (Fig.1). Scabies is transmitted by direct contact with an infected person, which is why it is most common among family members, people in nursing homes, prisons, children attending kindergartens or nurseries and among migrant refugees (1). ...
Context 2
... our patients we noted only one case of norwegian scabies. Pruritus is a characteristic symptom for scabies (2,3,10). It typically worsens at night due to warmth of the body underneath the linen (2,10). ...
Context 3
... predominant symptom is intense pruritus, often intensifying at night, caused by a delayed allergic reaction to the presence of the parasite itself, its faeces and eggs (1). The clinical features of scabies are papules with erosions and excoriations located around the wrists, fingers, elbows, armpits, genitals, torso and buttocks, in newborns and children lesions can also occur on the head and face (1) (Fig.1). Scabies is transmitted by direct contact with an infected person, which is why it is most common among family members, people in nursing homes, prisons, children attending kindergartens or nurseries and among migrant refugees (1). ...
Similar publications
Sarcoptic mange in dog represents a parasitic skin disease, caused by the Sarcoptes scabiei mite, characterized by intense pruritus, alopecia, crusts and scales. It is frecquently a problem in shelters or in big communities of animals, because it is a highly contagious disease. Our research consists of a case study of a dog, which was severely affe...
Citations
... Dis. Rep. 2023, 15 223 the hands, and soles of the feet are often affected in infants and very young children, but usually not in adults or older children [4][5][6][7]. ...
... In 2017, scabies was added to the World Health Organization list of Neglected Tropical Disease. It causes significant socioeconomic impacts and affects all ages, sexes and types of social class and educational levels, although the risk of transmission increases in areas where hygienic conditions are not optimal and in settings with high concentrations of people where skin-to skin contact is common, such as kindergartens, schools, hospitals, nursing homes, and other closed institutions (prisons, military and refugee camps, mental institutions, etc.) [7][8][9]. The diagnosis of a scabies infestation is usually made from the history and examination of the affected person. ...
Drug utilization studies can provide direct insights into how a drug is used in real-world conditions and can give a rough estimate of the proportion of the study population treated with it. In the present work, we examined the consumption of permethrin 5% cream in the four provinces of Galicia (a Spanish autonomous community) and described the seasonal variability and the annual evolution of its consumption between 2018 and 2021. A descriptive, cross-sectional, and retrospective study of the consumption of this drug, expressed in defined daily dose per 1000 inhabitants per day (DID), was carried out. The results obtained revealed differences between the amounts consumed in the four Galician provinces (p < 0.001). No specific geographical pattern was observed; however, the results suggested a marked seasonality and a slightly increasing global trend in the consumption of permethrin 5% cream throughout the study period. Since the only authorized indication of this drug in the study area is the treatment of scabies, this work may give an idea of the epidemiological situation of the disease in Galicia and serve to establish public health strategies against this parasitosis.
One of the most common and significant symptoms for skin disorders is pruritus. Additionally, it serves as a significant catalyst for the exacerbation or reoccurrence of skin diseases. Pruritus seriously affects patients' physical and mental health, and even the quality of life. It brings a heavy burden to the patients, the families, even the whole society. The pathogenesis and regulation mechanisms for pruritus are complicated and have not yet been elucidated. Previous clinical studies have shown that itch worsens at night in scabies, chronic pruritus, atopic dermatitis, and psoriasis, suggesting that skin pruritus may change with circadian rhythm. Cortisol, melatonin, core temperature, cytokines, and prostaglandins are the main regulatory factors of the circadian rhythm of pruritus. Recent studies have shown that some CLOCK genes, such as BMAL1, CLOCK, PER, and CRY, play an important role in the regulation of the circadian rhythm of pruritus by regulating the Janus tyrosine kinase (JAK)-signal transducer and activator of transcription (STAT) and nuclear factor kappa-B (NF-κB) signaling pathways. However, the mechanisms for circadian clock genes in regulation of circadian rhythm of pruritus have not been fully elucidated. Further studies on the mechanism of circadian clock genes in the regulation of circadian rhythm of pruritus will lay a foundation for elucidating the regulatory mechanisms for pruritus, and also provide new ideas for the control of pruritus and the alleviation of skin diseases.
