Fig 2 - uploaded by Joon Seong Lee
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Endoscopic view of the early gastric cancer showing an irregular and slightly raised lesion with central depression.
Source publication
Concern about detecting gastric carcinoma in its early stages has increased the incidence of detecting multiple synchronous gastric carcinomas. Although gastric carcinomas may present with various gross features, those showing the features of submucosal tumor (SMT) are rare. We report on a case of synchronous gastric carcinomas comprising one lesio...
Context in source publication
Context 1
... months duration. Physical examination and labo- ratory tests on admission revealed no abnormalities. EGD revealed a 1.0-cm SMT with a central ulceration on the fundus that had the typical "bridging fold" feature of an SMT ( Fig. 1). EGD also demonstrated an erythematous and minimally raised lesion with a central depression at the gastric angle (Fig. 2). Endoscopic ultrasound (EUS; GF-UM2000, Olympus, Tokyo, Japan) revealed that the SMT was a homogeneous, well-circumscribed, and hypo- echoic mass within the submucosal layer (Fig. 3), and that lymphadenopathy was not present. Furthermore, the lesion at the gastric angle was a hypoechoic thickening of the first sonographic layer of the ...
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Early detection and treatment decrease the mortality rate associated with gastric cancer (GC). However, the natural history of GC remains unclear. An 85-year-old woman was referred to our hospital for evaluation of a gastric tumor. Esophagogastroduodenoscopy identified a 6 mm, flat-elevated lesion at the lesser curvature of the antrum. A biopsy spe...
Citations
Subepithelial tumor-like gastric cancer (SET-like GC) is a special type of gastric cancer with a relatively low prevalence of approximately 1%. Diagnosing SET-like GC is challenging because the tumor is often covered with normal mucosa. The mechanisms of occurrence of SET-like GC include: 1) excessive infiltration of lymphocytes in the cancer, 2) intensive secretion of mucin by mucinous adenocarcinoma, 3) excessive fibrosis around the cancer, and 4) adenocarcinoma arising from heterotopic gastric glands in the submucosa. It is important to be aware of the endoscopic features of SET-like GC to differentiate it from other subepithelial tumors, to recognize the possibility of SET-like GC, and to make a diagnosis before treatment. In this review, we summarized the epidemiologic and clinicopathologic characteristics of SET-like GC.
