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Elements involved in amputation for NSTI (multivariate logistic regression analysis)

Elements involved in amputation for NSTI (multivariate logistic regression analysis)

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1. Abstract 1.1. Background: Necrotizing Soft Tissue Infections (NSTIs) cause rapid necrosis of soft tissue proximal to infected areas and are associated with a mortality rate of up to 35% depending on the type. However, there are no standardized procedures for determining treatment modality (i.e., debridement vs. amputation). 1.2. Methods: In this...

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... no significant differences were observed between the groups in the following criteria: qSO- did not show any significant differences, but the Lac value (p = 0.049) showed significant differences between the amputated and non-amputated groups (Table 1). Although there was a significant difference in the results of the binary logistic regression analysis of SOFA scores and Lac values between the groups, no significant differences were observed in the multivariate logistic regression analysis (p = 0.071, 0.330) ( Table 2). Glasgow coma scale; Glu, glucose; Hb, hemoglobin; HR, heart rate; Lac, arterial blood lactose; LRINEC, score laboratory risk indicator for necrotizing fasciitis score; MAP, mean arterial pressure; Plt, platelet count; P/F ratio, PaO2/FiO2 ratio; PT-INR, prothrombin time international normalized ratio; qSOFA, quick SOFA; sBP, systolic blood pressure; SI, shock index; SIRS, systemic inflammatory response syndrome; SOFA, sequential organ failure assessment; T.bil, Total bilirubin; WBC, white blood cell count. ...

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Article
Full-text available
1. Abstract 1.1. Background: Necrotizing Soft Tissue Infections (NSTIs) cause rapid necrosis of soft tissue proximal to infected areas and are associated with a mortality rate of up to 35% depending on the type. However, there are no standardized procedures for determin�ing treatment modality (i.e., debridement vs. amputation). 1.2. Methods: In...