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Effect of S. epidermidis lysate on epidermis thickness and keratinocyte numbers in human skin explant. (A) The total thickness of epidermal layers in the wound area as evaluated from H&E-stained human skin sections treated with S. epi lysate for diabetic and Non-diabetic samples (P = .03, P = .04, respectively, n = 3). (B) Cell number per unit area in the epidermis of wound area as evaluated from H&E-stained human skin sections after treatment. Significance was relative to control data indicated by * P < .05.
Source publication
Appropriate treatment of non-healing diabetic foot ulcers is challenging as the whole skin repair process is complicated. Current therapeutic strategies have to be evolved for better efficacy. Staphylococcus epidermidis (S. epidermidis) is a commensal having probiotic properties. The wound healing potential of its lysate was explored using skin bio...
