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Dosage forms in Unani system of medicine
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Fermentation in Unani System of Medicine has an important role in drug development.
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... These compounds can, therefore, be used along with chemotherapeutic drugs for reversing multidrug resistance 38 . Herbal drugs are much cheaper and safer for which about 80% of the world's population relies on herbal medicines as primary health care support 39 .These compounds possess strong antioxidant properties 40,41 . ...
... Herbal Essences as volatile, aromatic, and colorless materials with terpene and alcoholic origin have complex chemical compounds that are nowadays widely used in food, pharmaceutical, cosmetic, sanitary and chemical industries (Kumar and Zakir, 2019;McGaw et al., 2019;Yousefi et al., 2018). The division of effective drug substances into plants is the four main groups of alkaloids, glycosides, volatile oils, and other effective substances. ...
Conventional methods for extraction of the active constituents from herbal plants, in addition to their high processing costs, are harmful to the environment owing to their time and energy consumption, uncontrollable parameters, use of toxic and dangerous solvents, loss of the extract, thermal instability, the contamination of the product with organic solvents and the loss of water-soluble compounds, and venting Volatile Organic Compounds (VOC). The use of supercritical fluids, especially supercritical carbon dioxide, is the most suitable option for extracting active constituents from the herbal plants. In this study, Due to the abundance of "Urtica dioica" (nettle) and "Sambucus ebulus" (elderberry) in Guilan province and the presence of valuable substances in them, the active constituents of these two plants and their application, the method of planting and extracting their valuable substances have been studied. Various methods were applied to extract active constituents from these two plants. Supercritical CO2 is an attractive alternative process for traditional solvent extraction CO2 was used in a process, and then recovered to use again. There have been an increasing number of commercialized production plants utilizing supercritical fluids extraction process. This article summarized and presented this environmentally friendly process for the extraction of active constituents from herbal plants to replace traditional techniques to reduce the environmental impact of the extraction process.
There is an increasing awareness and general acceptability of indigenous drugs in today’s medical practice and over 80% of the world population depends on herbal drugs and products for healthy living due to their no side effects. Unani formulations are based on herbal, mineral, and animal origin and have been practiced in India for hundreds of years for treating various ailments by its holistic approach with natural means and drugs. Research is a creative work using existing knowledge for further development and advancement of knowledge and the approach, methodology and technique of research should be consistent with the ultimate objective because the scientific method of research is a combination of hypothesis, experimentation, observation, and reasoning. Therefore, the criteria of real scientific research are that its result should be reproducible under similar conditions. The paper deals with the objective of standardization and makes experimentation, and observation and particularly to check out Physico-chemical data of two in-house prepared samples of compound Unani formulation ArqAswadBaridunderSOP guidelines by adopting two different methods(classical and modern) of fermentation process separately and the content so obtained after distillation from fermented materials were utilized further to prepare two separate samples of the finished products i.e. Arq-e-Aswad Barid and underwent for the comparative assessment by following some Physico-chemical and quality control parameters like viscosity, specific gravity, refractive index, weight per ml, detection of aflatoxin, microbial load, pesticide residue, etc. of both the samples to achieve the objective of study. Besides, the preliminary physicochemical study of all ingredients used as raw material in the preparation of Arq-e-Aswad Barid was also conducted.
