Figure 2 - uploaded by Mohamed Bouhrim
Content may be subject to copyright.
Source publication
Introduction: Kidney stone is a major public health problem. Over 5% of the population is affected by kidney stones, with causes a lifetime risk of transmitting renal lithiasis of about 8 to 10%.
Objective: The goal of our study is the attitude and awareness of lithiasis patients regarding the use of medicinal plants in eastern Morocco.
Methods: We...
Contexts in source publication
Context 1
... most common methods used to treat kidney stones are ESWL lithotripsy and medication therapy [24]. In the present work, among 96% of the patients who consulted the doctor, 92% followed their medications treatment, while 8% of people did not follow the treatment (fig. 2a). On the other hand, among patients who followed their treatment, 53% confirmed that the medications treatment was effective, while 47 confirmed the ineffectiveness of the medications in the treatment ( fig. 2b). Studies have shown that there is no satisfactory medication to use in clinical treatment despite significant progress in ...
Context 2
... 96% of the patients who consulted the doctor, 92% followed their medications treatment, while 8% of people did not follow the treatment (fig. 2a). On the other hand, among patients who followed their treatment, 53% confirmed that the medications treatment was effective, while 47 confirmed the ineffectiveness of the medications in the treatment ( fig. 2b). Studies have shown that there is no satisfactory medication to use in clinical treatment despite significant progress in studying the biological and physical aspects of kidney stones. Also, despite the great development in the techniques used to break up the kidney stones, data indicate that exposure to shock waves in therapeutic ...
Context 3
... most common methods used to treat kidney stones are ESWL lithotripsy and medication therapy [24]. In the present work, among 96% of the patients who consulted the doctor, 92% followed their medications treatment, while 8% of people did not follow the treatment (fig. 2a). On the other hand, among patients who followed their treatment, 53% confirmed that the medications treatment was effective, while 47 confirmed the ineffectiveness of the medications in the treatment ( fig. 2b). Studies have shown that there is no satisfactory medication to use in clinical treatment despite significant progress in ...
Context 4
... 96% of the patients who consulted the doctor, 92% followed their medications treatment, while 8% of people did not follow the treatment (fig. 2a). On the other hand, among patients who followed their treatment, 53% confirmed that the medications treatment was effective, while 47 confirmed the ineffectiveness of the medications in the treatment ( fig. 2b). Studies have shown that there is no satisfactory medication to use in clinical treatment despite significant progress in studying the biological and physical aspects of kidney stones. Also, despite the great development in the techniques used to break up the kidney stones, data indicate that exposure to shock waves in therapeutic ...
Context 5
... most common methods used to treat kidney stones are ESWL lithotripsy and medication therapy [24]. In the present work, among 96% of the patients who consulted the doctor, 92% followed their medications treatment, while 8% of people did not follow the treatment (fig. 2a). On the other hand, among patients who followed their treatment, 53% confirmed that the medications treatment was effective, while 47 confirmed the ineffectiveness of the medications in the treatment ( fig. 2b). Studies have shown that there is no satisfactory medication to use in clinical treatment despite significant progress in ...
Context 6
... 96% of the patients who consulted the doctor, 92% followed their medications treatment, while 8% of people did not follow the treatment (fig. 2a). On the other hand, among patients who followed their treatment, 53% confirmed that the medications treatment was effective, while 47 confirmed the ineffectiveness of the medications in the treatment ( fig. 2b). Studies have shown that there is no satisfactory medication to use in clinical treatment despite significant progress in studying the biological and physical aspects of kidney stones. Also, despite the great development in the techniques used to break up the kidney stones, data indicate that exposure to shock waves in therapeutic ...
Similar publications
Medicinal plants are commonly used in the treatment of diabetes, particularly as they contain flavonoids and phenolic compounds. The present study aims to investigate the activities of a polyherbal formulation made from Urtica dioica, Apium graveolens, and Zingiber officinale (UAZ) against streptozotocin–nicotinamide ((STZ-NA)-induced type 2 diabet...
Citations
... The most commonly cited plants by the patients; are Citrus limon, Petroselinum sativum, Herniaria hirsuta and Olea Europea, which have been used in Moroccan traditional pharmacopoeia to treat hypertension, and urinary disorders such as lithiasis. Also known to have been prescribed for cardiovascular diseases, hypercholesterolemia, diabetes and dermatological care (Abouri et al., 2012;Arrout et al., 2022;Bellakhdar, 1997b;Charles, 2012;Eddouks et al., 2017Eddouks et al., , 2002El Guerrouj et al., 2021;Jouad et al., 2001;Khouchlaa et al., 2017;Zougagh et al., 2019). The plant species of Apiaceae have been widely used in the treatment of digestive disorders, whereas those included in Lamiaceae are known for their physiological properties due to their constituents of flavonoids and phenols (Aćimović et al., 2016;Asghari et al., 2017). ...
... Herbal medicine is an integral part of the cultural practices of our local communities, which constitute an important heritage for the management of urological diseases Guerrouj et al., 2021). In recent years, various plants and traditional medicines have been proposed to reduce calcium oxalate kidney stones, which can be useful in its prevention and treatment (Afkari et al., 2019). ...
... Herbal medicine is an integral part of the cultural practices of our local communities, which constitute an important heritage for the management of urological diseases Guerrouj et al., 2021). In recent years, various plants and traditional medicines have been proposed to reduce calcium oxalate kidney stones, which can be useful in its prevention and treatment (Afkari et al., 2019). ...
Background: Nephrolithiasis, also known as kidney stones, is the third most prevalent issue affecting the urinary tract, following urinary tract infections and prostate illnesses. Approximately 12% of the global population experiences this condition at some point, encompassing individuals of all ages, genders, and races. Regrettably, the current medical landscape lacks a pharmacological intervention that can effectively treat or prevent the recurrence of kidney stones. Consequently, people turn to herbal medicine as a viable option. Aim: Evaluate the use and perception of herbal medicine among patients residing in Karbala, documenting their herbal products and evaluating patients' knowledge, practice, and attitude toward herbal remedies and possible factors behind using herbal remedies as an alternative to conventional medications. Method: Two-hundred and sixty-six patients diagnosed with kidney stones in Karbala joined this survey, a cross-sectional design between October 2022 and March 2023, using a questionnaire administered to patients. In face-to-face meetings, participants completed a multicomponent questionnaire comprising 26 items in three parts. The data acquired were analyzed using a statistical package for social sciences; Chi-square was used to correlate some variables, and P-values of <0.05 were considered significant. Results: A significant proportion of individuals aged 20 to 49 exhibited a high level of education, with 50.8% possessing a university degree. Conversely, 9.4% of patients were illiterate. Most individuals within the sample were employed, with only 7.5% identified as students and 4.5% classified as jobless. Most participants, precisely 76.3%, were found to be married, while a smaller proportion, approximately 18.4%, were identified as unmarried. A mere 5.3% of the individuals under consideration were identified as widows, whereas there were no instances of divorce among them. The present study evaluated patients' knowledge, attitudes, and practice (KAP) outcomes, revealing suboptimal levels of knowledge, neutral attitudes, and poor practice toward herbal therapy. Moreover, the data analysis revealed a noteworthy association between educational attainment and knowledge score, as well as gender and attitude toward herbal products. The findings additionally documented twelve herbal medicines used by patients, with Zea mays and Barley emerging as the most often employed remedies among the remaining options. Conclusion: Most patients lack proper knowledge regarding herbal remedies, and most seek herbal products due to their low cost, relative recommendation, and belief that herbal medications are safe. The most used treatments were Zea mays and barley, which were reasonably priced and famous for their use.
Objective:
The main purpose of the present work was to determine the chemical composition, safety, and antioxidant and antihyperlipidemic activities of an aqueous extract of Teucrium takoumitense.
Methods:
Phytochemical analysis (total phenolic, total flavonoid, and total hydroxycinnamic acid contents), antioxidant activity (ferric-reducing antioxidant power, 2,2'-azino-bis(3-ethylbenzothiazoline-6-sulphonic acid, 2,2-diphenyl-1-picrylhydrazil, and total antioxidant capacity tests), acute toxicity, and antihyperlipidemic activity were evaluated according to established models. In addition, the phytochemical profile was determined by methylation followed by gas chromatography-mass spectrometry (GC/MS).
Results:
The aqueous extract of T. takoumitense had a high content of total polyphenols (87.01 ± 0.31 mg gallic acid equivalent (GAE)/g extract) and hydroxycinnamic acid (2.28 ± 0.1 g/100 g Powdered Material) and a low content of total flavonoids (2.99 ± 0.16 mg GAE/g extract). In addition, the extract demonstrated remarkable antioxidant activity (DPPH IC50 = 76.67 ± 0.56 μg/mL, ABTS IC50 = 89.65 ± 0.27 μg/mL, FRAP EC50 = 296.32 ± 0.86 μg/mL, TAC value = 43 ± 0.27 mg EAA/g extract). The main compounds were identified as benzene, (hexyloxy)- (19.32%), 2,6a-methano-6aH-indeno[4,5-b]oxirene, octahedro-(1a.alpha., 2.beta., 3a.alpha., 6a.beta., 6b.alpha.)- (32.42%), d-fucose (5.47%), 5-hydroxymethylfurfural (5.47%) and guaiacol (3.19%). The LD50 was estimated to be between 500 and 2000 mg/kg. Furthermore, at 500 and 250 mg/kg, the aqueous extract of T. takoumitense exhibited good antihyperlipidemic activity in vivo.
Conclusion:
T. takoumitense extract has significant pharmacological potential and a varied chemical composition.
