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Different configurations of venovenous ECMO (VV-ECMO) circuit. A, Conventional VV-ECMO circuit with reinfusion cannulation of the right common femoral vein and drainage cannulation of the left common femoral vein. B, Veno-VV-ECMO circuit with reinfusion cannulation of the right internal jugular vein and bilateral femoral vein drainage cannulation connected via "Y" configuration. C, Two VV-ECMO circuits arranged in parallel with each femoral vein drainage cannula draining into 2 separate ECMO circuits.

Different configurations of venovenous ECMO (VV-ECMO) circuit. A, Conventional VV-ECMO circuit with reinfusion cannulation of the right common femoral vein and drainage cannulation of the left common femoral vein. B, Veno-VV-ECMO circuit with reinfusion cannulation of the right internal jugular vein and bilateral femoral vein drainage cannulation connected via "Y" configuration. C, Two VV-ECMO circuits arranged in parallel with each femoral vein drainage cannula draining into 2 separate ECMO circuits.

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Context 1
... femoral vein drainage cannulas were connected in a "Y" configuration to create a single drainage circuit. A 20-French reinfusion cannula was placed in the right atrium through the right internal jugular vein (Figure 1, B). While the reconfigured veno-VV-ECMO circuit successfully increased the flows to 6 to 6.5 L/min, the patient's hypoxemia was not corrected (PaO 2 /FIO 2 of 48 mm Hg) and lactate dehydrogenase was elevated (>1400 units/L). ...
Context 2
... was connected to the second ECMO circuit with both circuits now reinfusing into the existing reinfusion cannula (Figure 1, C). With 2 VV-ECMO circuits arranged in parallel, a combined flow of 6 L/min was achieved with each circuit providing 3 L/min of flow. ...