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Gene Expression (GE) data have been attracting researchers since ages by virtue of the essential genetic information they carry, that plays a pivotal role in both causing and curing terminal ailments. GE data are generated using DNA microarrays. These gene expression data are obtained in measurements of thousands of genes with relatively very few s...
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Background
Immune-related adverse events (irAEs) comprise a distinct spectrum of auto-inflammatory manifestations triggered due to immune checkpoint inhibitors (ICI). Current data on the association of irAEs with outcomes in NSCLC treated with nivolumab are limited.Methods and objectivesWe pooled data from 531 metastatic NSCLC patients from five ce...
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secondary school students in Kuala Terengganu on bullying
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analysis. A total of 405 participants from secondary school
students around the Kuala Terengganu area responded...
Since late December 2019 a new epidemic outbreak has emerged from Whuhan, China. Rapidly the new coronavirus has spread worldwide. China CDC has reported results of a descriptive exploratory analysis of all cases diagnosed until the 11th February 2020, presenting the epidemiologic curves and geo-temporal spread of COVID-19 along with case fatality...
Background
Potential effects of different doses of specific fish collagen peptides (Naticol®) on the signs of skin ageing were firstly assessed in double-blind, randomised and placebo controlled clinical studies. The studies showed benefits of fish collagen peptides (Naticol®) on skin firmness, skin hydration and wrinkle appearance. In addition to...
Jet quenching provides a very flexible variety of observables which are sensitive to different energy- and time-scales of the strongly interacting matter created in heavy-ion collisions. Exploiting this versatility would make jet quenching an excellent chronometer of the yoctosecond structure of the evolution process. Here we show, for the first ti...
Citations
... 8 [56] One of the studies, which utilizes the CNN-convolutional-neural-networks been under optimization with the other approaches like ACO-ant-colony optimization. The PCO-particle-swarm optimization technique is implemented in the study. ...
Big-data research studies relying upon Deep-learning methods are revitalized the decision-making mechanism in the business sectors and the enterprise domains. The firms’ operational parameters also have the dependency of the Big-data analytics phase, their way of managing the data, and to evolve the outcomes of Big-data implementation by using the Deep-learning algorithms. Deep-learning approaches enhancements in Big-data applications facilitate the decision-making process such as the information-processing to the employees, analytical potentials augmentation, and in the transition of more innovative work. In this DL-approach, the robust-patterns of the data-predictions resulted from the unstructured information by conceptualizing the Decision-making methods. Hence this paper reviewed the impact of the Deep-learning process utilizing the Big-data in the enterprise and Business sectors. Also this study provides a comprehensive survey of all the Deep-learning techniques illustrating the efficiency of Big-Data processing and their impacts of operational parameters. Further it concentrating the data-dimensionality factors and the Big-data complications rectifying by utilizing the DL-algorithms, usage of Machine-learning or deep-learning process for the decision-making mechanism in the Enterprise sectors and business sectors. This research discussed the predictions of the Big-data analytics resulting to the decision parameters within the organisations, and in the management of larger scale of datasets in Big-data analytics processing by utilizing the Deep-learning implementations. The comparative analysis of the reviewed studies has also been described by comparing existing approaches of Deep-learning methodologies in employing Big-data analytics.
... These experiments utilize the CityPulse-tra c dataset and the Citypulse pollution datasets. Advantages and Disadvantages 9 [53] One of the studies, which utilizes the CNN-convolutional-neural-networks been under optimization with the other approaches like ACO-ant-colony optimization. The PCO-particle-swarm optimization technique is implemented in the study. ...
The present elaboration of Big-data research studies relying upon Deep-learning methods had revitalized the decision-making mechanism in the business sectors and the enterprise domains. The firms' operational parameters also have the dependency of the Big-data analytics phase, their way of managing the data, and to evolve the outcomes of Big-data implementation by using the Deep-learning algorithms. The present enhancements in the Deep-learning approaches in Big-data applications facilitate the decision-making process such as the information-processing to the employees, analytical potentials augmentation, and in the transition to having more innovative work. In this DL-approach, the robust-patterns of the data-predictions resulted from the unstructured information by conceptualizing the Decision-making methods. Hence this paper elaborates the above statements stating the impact of the Deep-learning process utilizing the Big-data to operate in the enterprise and Business sectors. Also this study provides a comprehensive survey of all the Deep-learning techniques illustrating the efficiency of Big-Data processing on having the impacts of operational parameters, concentrating the data-dimensionality factors and the Big-data complications rectifying by utilizing the DL-algorithms, usage of Machine-learning or deep-learning process for the decision-making mechanism in the Enterprise sectors and business sectors, the predictions of the Big-data analytics resulting to the decision parameters within the organisations, and in the management of larger scale of datasets in Big-data analytics processing by utilizing the Deep-learning implementations. The comparative analysis of the reviewed studies has also been described by comparing existing approaches of Deep-learning methodologies in employing Big-data analytics.
... The analysis and accurate interpretation of biological information is crucial because, in such data, the number of variables (genes and their coded products) is many times greater than the number of tested samples. The challenge in genomic data is in applying appropriate computational methods to the ever-increasing size of high-throughput multiomics data [10]. Processing and integration of multiomics data requires in-depth technical and biological knowledge of how these data are generated [11]. ...
Biomedical institutions rely on data evaluation and are turning into data factories. Big-data storage centers, supercomputing systems, and increased algorithmic efficiency allow us to analyze the ever-increasing amount of data generated every day in biomedical research centers. In network science, the principal intrinsic problem is how to integrate the data and information from different experiments on genes or proteins. Data curation is an essential process in annotating new functional data to known genes or proteins, undertaken by a biobank curator, which is then reflected in the calculated networks. We provide an example of how protein–protein networks today have space-time limits. The next step is the integration of data and information from different biobanks. Omics data and networks are essential parts of this step but also have flawed protocols and errors. Consider data from patients with cancer: from biopsy procedures to experimental tests, to archiving methods and computational algorithms, these are continuously handled so require critical and continuous “updates” to obtain reproducible, reliable, and correct results. We show, as a second example, how all this distorts studies in cellular hepatocellular carcinoma. It is not unlikely that these flawed data have been polluting biobanks for some time before stringent conditions for the veracity of data were implemented in Big data. Therefore, all this could contribute to errors in future medical decisions.
Health is so important for human beings. Thanks to the technological developments both in medicine and information technologies, the success percentages of both medical diagnosing and medical treatment systems are increasing day by day. Cancer is the most common causes of death in today’s world and is generally diagnosed at the last stages. Cancer has many types such as breast cancer, skin cancer, leukemia and etc. Diagnosis of cancer at early stages is very important for the success of medical treatments. The aim of this study was to evaluate the classification performances of some popular algorithms on the way to design an efficient computer aided breast and/or skin cancer diagnosing system to support the doctors and patients. For this purpose, same machine learning and deep learning algorithms were applied on immunotherapy dataset and breast cancer Coimbra dataset from UCI machine learning data repository. Feature selection by information gain and reliefF were applied on datasets before classification in order to increase the efficiency of classification processes. Support Vector Machines (SVM), Random Forest (RF), Recurrent Neural Network (RNN) and Convolutional Neural Network (CNN) algorithms were used for classification experiments. Accuracy values are used for performance metric. According to these results, RNN has shown the best performance among the others with 92% on both datasets. This shows that deep learning algorithms especially RNN has great potential to diagnose the cancer from dataset with high success ratios.
